This database contains 343 studies, archived under the term: "therapy"
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Transcranial Magnetic Stimulation to Address Mild Cognitive Impairment in the Elderly: A Randomized Controlled Study
Drumond Marra, Hellen Livia,
Myczkowski, Martin Luiz,
Maia Memória, Cláudia,
Arnaut, Débora,
Leite Ribeiro, Philip,
Sardinha Mansur, Carlos Gustavo,
Lancelote Alberto, Rodrigo,
Boura Bellini, Bianca,
Alves Fernandes da Silva, Adriano,
Tortella, Gabriel,
Ciampi de Andrade, Daniel,
Teixeira, Manoel Jacobsen,
Forlenza, Orestes Vicente,
Marcolin, Marco Antonio
Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique with potential to improve memory. Mild cognitive impairment (MCI), which still lacks a specific therapy, is a clinical syndrome associated with increased risk of dementia. This study aims to assess the effects of high-frequency repetitive TMS (HF rTMS) on everyday memory of the elderly with […]
The PACE study: a randomized clinical trial of cognitive activity strategy training for older people with mild cognitive impairment
Vidovich, Mandy R.,
Lautenschlager, Nicola T.,
Flicker, Leon,
Clare, Linda,
McCaul, Kieran,
Almeida, Osvaldo P.
Objective: The role of cognition-focused interventions in reducing cognitive decline in older people remains uncertain. This study aimed to clarify whether a group cognitive activity (CA) strategy-training program would decrease the 2-year rate of cognitive decline of people with mild cognitive impairment (MCI).; Design: Randomized controlled trial.; Setting: One study site.; Participants: 160 older adults […]
Aerobic exercise increases hippocampal volume in older women with probable mild cognitive impairment: a 6-month randomised controlled trial
ten Brinke, Lisanne F.,
Bolandzadeh, Niousha,
Nagamatsu, Lindsay S.,
Hsu, Chun Liang,
Davis, Jennifer C.,
Miran-Khan, Karim,
Liu-Ambrose, Teresa
Background: Mild cognitive impairment (MCI) is a well-recognised risk factor for dementia and represents a vital opportunity for intervening. Exercise is a promising strategy for combating cognitive decline by improving brain structure and function. Specifically, aerobic training (AT) improved spatial memory and hippocampal volume in healthy community-dwelling older adults. In older women with probable MCI, […]
Impact of ambient bright light on agitation in dementia
Barrick, Ann Louise,
Sloane, Philip D.,
Williams, Christianna S.,
Mitchell, C. Madeline,
Connell, Bettye Rose,
Wood, Wendy,
Hickman, Susan E.,
Preisser, John S.,
Zimmerman, Sheryl
Objective: To evaluate the effect of ambient bright light therapy (BLT) on agitation among institutionalized persons with dementia. Methods: High intensity, low glare ambient lighting was installed in activity and dining areas of a state psychiatric hospital unit in North Carolina and a dementia-specific residential care facility in Oregon. The study employed a cluster-unit crossover […]
Mild cognitive impairment disease treated with electroacupuncture: a multi-center randomized controlled trial
Zhao, Ling,
Zhang, Fu-Wen,
Zhang, Hong,
Zhao, Yu,
Zhou, Bo,
Chen, Wei-Yin,
Zhu, Man-Jia
Objective: To verify the clinical efficacy on mild cognitive impairment (MCI) treated with electroacupuncture (EA) intervention based on the principle as “promoting the circulation of the Governor Vessel and regulating the marrow” and plan to provide the A-grade evidence of the evidence-based medicine for the clinical treatment of this disease with acupuncture and moxibustion.; Methods: […]
FMRI connectivity analysis of acupuncture effects on the whole brain network in mild cognitive impairment patients
Feng, Yuanyuan,
Bai, Lijun,
Ren, Yanshuang,
Chen, Shangjie,
Wang, Hu,
Zhang, Wensheng,
Tian, Jie
The increased risk for the elderly with mild cognitive impairment (MCI) to progress to Alzheimer’s disease makes it an appropriate condition for investigation. While the use of acupuncture as a complementary therapeutic method for treating MCI is popular in certain parts of the world, the underlying mechanism is still elusive. We sought to investigate the […]
Differences in verbal memory performance in postmenopausal women receiving hormone therapy: 17β-estradiol versus conjugated equine estrogens
Wroolie, Tonita E.,
Kenna, Heather A.,
Williams, Katherine E.,
Powers, Bevin N.,
Holcomb, Megan,
Khaylis, Anna,
Rasgon, Natalie L.
Objective: Much controversy exists and many questions remain unanswered about the effects of hormone therapy (HT) on cognition in postmenopausal women. There is growing evidence suggesting that HT compounds containing conjugated equine estrogen (CEE) have negative effects on cognition whereas 17β-estradiol (17β-E) either has positive or neutral effects. The present study sought to further examine […]