This database contains 283 studies, archived under the term: "diagnosis"
Click here to filter this large number of results.
The mini-mental Parkinson’s (MMP) as a cognitive screening tool in people with Parkinson’s disease
Caslake, Robert,
Summers, Fiona,
McConachie, Douglas,
Ferris, Catriona,
Gordon, Joanna,
Harris, Clare,
Caie, Linda,
Counsell, Carl
Background: Cognitive decline is common in Parkinson’s disease (PD) but may not be adequately identified by the mini-mental state examination (MMSE), which is better suited to Alzheimer’s disease. The mini-mental Parkinson (MMP) examination is a cognitive screening tool designed in French specifically for PD. We aimed to establish the validity and reliability of the English […]
Evidence for neurocognitive plasticity in at-risk older adults: the experience corps program
Carlson, M. C.,
Erickson, K. I.,
Kramer, A. F.,
Voss, M. W.,
Bolea, N.,
Mielke, M.,
McGill, S.,
Rebok, G. W.,
Seeman, T.,
Fried, L. P.
Objective: To determine whether Experience Corps (EC), a social service program, would improve age-vulnerable executive functions and increase activity in brain regions in a high-risk group through increased cognitive and physical activity.; Methods: Eight community-dwelling, older female volunteers and nine matched wait-list controls were recruited to serve in the ongoing EC: Baltimore program in three […]
Diagnosis of Alzheimer’s disease patients with rapid cognitive decline in clinical practice: interest of the Deco questionnaire
Carcaillon, L.,
Berrut, G.,
Sellal, F.,
Dartigues, J. F.,
Gillette, S.,
Pere, J. J.,
Bourdeix, I.
Background: Patients with Alzheimer’s disease (AD) who deteriorate rapidly are likely to have a poorer prognosis. There is a clear need for a clinical assessment tool to detect such a decline in newly diagnosed patients.; Objective: To identify the predictive factors of rapid cognitive decline (RCD) in a cohort of patients with mild to moderate […]
Promoting health in early-stage dementia: evaluation of a 12-week course
This project tested a 12-week health promotion course for older adults with early-stage dementia. In a quasi-experimental design, participants were assigned by site to intervention group or control group and evaluated at two time points. Mini-Mental State Examination scores, Geriatric Depression Scale scores, health behaviors, plus several measures of psychological well-being were used in this […]
Validation of Alzheimer’s disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer’s Disease Neuroimaging Initiative (E-ADNI)
Buerger, Katharina,
Frisoni, Giovanni,
Uspenskaya, Olga,
Ewers, Michael,
Zetterberg, Henrik,
Geroldi, Cristina,
Binetti, Giuliano,
Johannsen, Peter,
Rossini, Paolo Maria,
Wahlund, Lars-Olof,
Vellas, Bruno,
Blennow, Kaj,
Hampel, Harald
Background: Alzheimer’s Disease Neuroimaging Initiatives (“ADNI”) aim to validate neuroimaging and biochemical markers of Alzheimer’s disease (AD). Data of the pilot European-ADNI (E-ADNI) biological marker programme of cerebrospinal fluid (CSF) and plasma candidate biomarkers are reported.; Methods: Six academic EADC centres recruited 49 subjects (healthy controls, subjects with mild cognitive impairment (MCI) and AD). We […]
A sensitivity comparison of clinical tests for postural instability in patients with Huntington’s disease
Brožová, Hana,
Štochl, Jan,
Klempíř, Jiří,
Kucharík, Martin,
Růžička, Evžen,
Roth, Jan
Falls are a common complication in Huntington’s disease (HD) and detection of postural instability (PI) may be useful for identifying patients who are at risk of falls. The aim of our study was to find the most sensitive clinical test for PI in patients with HD and to correlate PI with the other symptoms. 20 […]
Depression as a risk factor or prodromal feature for dementia? Findings in a population-based sample of Swedish twins
Brommelhoff, Jessica A.,
Gatz, Margaret,
Johansson, Boo,
McArdle, John J.,
Fratiglioni, Laura,
Pedersen, Nancy L.
This study tested whether history of depression is associated with an increased likelihood of dementia, and whether a first depressive episode earlier in life is associated with increased dementia risk, or whether only depressive episodes close in time to dementia onset are related to dementia. Depression information came from national hospital discharge registries, medical history, […]
A combination of CSF tau ratio and midsaggital midbrain-to-pons atrophy for the early diagnosis of progressive supranuclear palsy
Borroni, Barbara,
Malinverno, Matteo,
Gardoni, Fabrizio,
Grassi, Mario,
Parnetti, Lucilla,
Agosti, Chiara,
Alberici, Antonella,
Premi, Enrico,
Bonuccelli, Ubaldo,
Gasparotti, Roberto,
Calabresi, Paolo,
Di Luca, Monica,
Padovani, Alessandro
Cerebrospinal fluid (CSF) tau ratio decrease (33kDa/55kDa forms) and mid-saggital midbrain-to-pons (MP) atrophy have been suggested as diagnostic markers for progressive supranuclear palsy (PSP). The usefulness of their combined evaluation has never been tested. We evaluated the CSF tau ratio and the MP atrophy as a combined marker for early identification of PSP. A total […]