This database contains 477 studies, archived under the term: "Non-pharmacological Treatment"
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Effects of multicomponent exercise on cognitive function in older adults with amnestic mild cognitive impairment: a randomized controlled trial
Suzuki, Takao,
Shimada, Hiroyuki,
Makizako, Hyuma,
Doi, Takehiko,
Yoshida, Daisuke,
Tsutsumimoto, Kota,
Anan, Yuya,
Uemura, Kazuki,
Lee, Sangyoon,
Park, Hyuntae
Background: To examine the effects of a multicomponent exercise program on the cognitive function of older adults with amnestic mild cognitive impairment (aMCI).; Design: Twelve months, randomized controlled trial;; Setting: Community center in Japan;; Participants: Fifty older adults (27 men) with aMCI ranging in age from 65 to 93 years (mean age, 75 years);; Intervention: […]
Cognitive behavioural therapy (CBT) for anxiety in people with dementia: study protocol for a randomised controlled trial
Spector, Aimee,
Orrell, Martin,
Lattimer, Miles,
Hoe, Juanita,
King, Michael,
Harwood, Kate,
Qazi, Afifa,
Charlesworth, Georgina
Background: Many people with dementia experience anxiety, which can lead to decreased independence, relationship difficulties and increased admittance to care homes. Anxiety is often treated with antipsychotic medication, which has limited efficacy and serious side effects. Cognitive behavioural therapy (CBT) is widely used to treat anxiety in a range of populations, yet no RCTs on […]
Increased cerebral metabolism after 1 year of deep brain stimulation in Alzheimer disease
Smith, Gwenn S.,
Laxton, Adrian W.,
Tang-Wai, David F.,
McAndrews, Mary Pat,
Diaconescu, Andreea Oliviana,
Workman, Clifford I.,
Lozano, Andres M.
Background: The importance of developing unique, neural circuitry-based treatments for the cognitive and neuropsychiatric symptoms of Alzheimer disease (AD) was the impetus for a phase I study of deep brain stimulation (DBS) in patients with AD that targeted the fornix.; Objective: To test the hypotheses that DBS would increase cerebral glucose metabolism in cortical and […]
A new frontier in spaced retrieval memory training for persons with Alzheimer’s disease
The objective of this pilot study was to investigate how a memory training technique called “Spaced Retrieval” (SR) might be effectively applied in helping persons with Alzheimer’s disease improve their recall of recent events. Capitalising on the interdependence among spared and impaired memory systems, it was hypothesised that SR training with support at encoding and […]
Effectiveness of dementia follow-up care by memory clinics or general practitioners: randomised controlled trial
Meeuwsen, Els J.,
Melis, René J. F.,
Van Der Aa, Geert C. H. M.,
Golüke-Willemse, Gertie A. M.,
De Leest, Benoit J. M.,
Van Raak, Frank H. J. M.,
Schölzel-Dorenbos, Carla J M,
Verheijen, Desiree C. M.,
Verhey, Frans R.J.,
Visser, Marieke C.,
Wolfs, Claire A.,
Adang, Eddy M. M.,
Olde Rikkert, Marcel G. M.
Objective: To examine the effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared with general practitioners.; Design: Multicentre randomised controlled trial.; Setting: Nine memory clinics and 159 general practitioners in the Netherlands.; Participants: 175 patients with a new diagnosis of mild to moderate dementia living in the community and their informal […]
An inpatient rehabilitation model of care targeting patients with cognitive impairment
McGilton, Katherine S.,
Davis, Aileen,
Mahomed, Nizar,
Flannery, John,
Jaglal, Susan,
Cott, Cheryl,
Naglie, Gary,
Rochon, Elizabeth
Background: The course and outcomes of hip fracture patients are often complicated by the presence of dementia and delirium, referred to as cognitive impairment (CI), which limits access to in-patient rehabilitation. In response to this concern, members of our team developed and piloted an in-patient rehabilitation model of care (Patient-Centred Rehabilitation Model; PCRM) targeting patients […]