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Effectiveness of dementia follow-up care by memory clinics or general practitioners: randomised controlled trial


Meeuwsen, Els J., Melis, René J. F., Van Der Aa, Geert C. H. M., Golüke-Willemse, Gertie A. M., De Leest, Benoit J. M., Van Raak, Frank H. J. M., Schölzel-Dorenbos, Carla J M, Verheijen, Desiree C. M., Verhey, Frans R.J., Visser, Marieke C., Wolfs, Claire A., Adang, Eddy M. M., Olde Rikkert, Marcel G. M.


BMJ (Clinical Research Ed.), Volume: 344, Pages.: e3086-e3086

Year of Publication



Objective: To examine the effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared with general practitioners.; Design: Multicentre randomised controlled trial.; Setting: Nine memory clinics and 159 general practitioners in the Netherlands.; Participants: 175 patients with a new diagnosis of mild to moderate dementia living in the community and their informal caregivers.; Interventions: Usual care provided by memory clinic or general practitioner.; Main Outcome Measures: Caregiver rated quality of life of the patient measured with the quality of life in Alzheimer’s disease instrument and self perceived burden of the informal caregiver measured with the sense of competence questionnaire (intention to treat analysis).; Results: The quality of life of the patients in the memory clinic group was 0.5 (95% confidence interval -0.7 to 1.6) points higher than in the general practitioner group. Caregivers’ burden was 2.4 (-5.8 to 1.0) points lower in the memory clinic group than in the general practitioner group.; Conclusion: No evidence was found that memory clinics were more effective than general practitioners with regard to post-diagnosis treatment and coordination care for patients with dementia. Without further evidence on the effectiveness of these modalities, other arguments, such as cost minimisation, patients’ preferences, or regional health service planning, can determine which type of dementia care is offered.; Trial Registration: Clinical trials NCT00554047.;

Bibtex Citation

@article{Meeuwsen_2012, doi = {10.1136/bmj.e3086}, url = {}, year = 2012, month = {may}, publisher = {{BMJ}}, volume = {344}, number = {may15 1}, pages = {e3086--e3086}, author = {E. J. Meeuwsen and R. J. F. Melis and G. C. H. M. Van Der Aa and G. A. M. Goluke-Willemse and B. J. M. De Leest and F. H. J. M. Van Raak and C. J. M. Scholzel-Dorenbos and D. C. M. Verheijen and F. R. J. Verhey and M. C. Visser and C. A. Wolfs and E. M. M. Adang and M. G. M. Olde Rikkert}, title = {Effectiveness of dementia follow-up care by memory clinics or general practitioners: randomised controlled trial}, journal = {{BMJ}} }


aged, aged, 80 and over, ambulatory care, cost of illness, dementia, female, followup studies, general practice, humans, male, middle aged, netherlands, outcome assessment (health care), quality of life, therapy

Countries of Study


Types of Dementia

Dementia (general / unspecified)

Types of Study

Randomised Controlled Trial

Type of Outcomes

Carer Burden (instruments measuring burden), Quality of Life of Person With Dementia


Primary Care, Specialist Dementia Centre Care / Memory Clinic

Type of Interventions

Non-pharmacological Treatment

Non-Pharmaceutical Interventions

Memory clinic / assessment centre