This database contains 384 studies, archived under the term: "Other"
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Increasing walking and bright light exposure to improve sleep in community-dwelling persons with Alzheimer’s disease: results of a randomized, controlled trial
McCurry, Susan M.,
Pike, Kenneth C.,
Vitiello, Michael V.,
Logsdon, Rebecca G.,
Larson, Eric B.,
Teri, Linda
Objectives: To test the effects of walking, light exposure, and a combination intervention (walking, light, and sleep education) on the sleep of persons with Alzheimer’s disease (AD).; Design: Randomized, controlled trial with blinded assessors.; Setting: Independent community living.; Participants: One hundred thirty-two people with AD and their in-home caregivers.; Interventions: Participants were randomly assigned to […]
Dementia caregivers’ responses to 2 Internet-based intervention programs
Purpose: The aim of this study was to examine the impact on dementia caregivers’ experienced stress and health status of 2 Internet-based intervention programs.; Design and Methods: Ninety-one dementia caregivers were given the choice of being involved in either an Internet-based chat support group or an Internet-based video conferencing support group. Pre-post outcome measures focused […]
Down syndrome and dementia: a randomized, controlled trial of antioxidant supplementation
Lott, Ira T.,
Doran, Eric,
Nguyen, Vinh Q.,
Tournay, Anne,
Head, Elizabeth,
Gillen, Daniel L.
Individuals with Down syndrome over age 40 years are at risk for developing dementia of the Alzheimer type and have evidence for chronic oxidative stress. There is a paucity of treatment trials for dementia in Down syndrome in comparison to Alzheimer disease in the general (non-Down syndrome) population. This 2-year randomized, double-blind, placebo-controlled trial assessed […]
Persons with mild or moderate Alzheimer’s disease learn to use urine alarms and prompts to avoid large urinary accidents
Lancioni, Giulio E.,
Singh, Nirbhay N.,
O’Reilly, Mark F.,
Sigafoos, Jeff,
Bosco, Andrea,
Zonno, Nadia,
Badagliacca, Francesco
This study assessed whether three patients with Alzheimer’s disease could learn to use urine alarms and caregivers’ prompts to eliminate large urinary accidents. As soon as the patient began to release urine, the alarm system presented auditory and vibratory signals. In relation to those signals, the caregiver would prompt/encourage the patient to stop urinating and […]
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people
Kwok, T.,
Lee, J.,
Law, C. B.,
Pan, P. C.,
Yung, C. Y.,
Choi, K. C.,
Lam, L. C.
Introduction: Whether homocysteine lowering by B vitamins can reduce cognitive decline in Alzheimer disease and vascular dementia patients is unclear.; Methods and Materials: 140 subjects with mild to moderate Alzheimer disease or vascular dementia were randomly assigned to take 1 mg of methylcobalamin and 5 mg of folic acid, or placebo once daily for 24 […]
Pilot study of a nonpharmacological intervention for delirium superimposed on dementia
Kolanowski, Ann M.,
Fick, Donna M.,
Clare, Linda,
Steis, Melinda,
Boustani, Malaz,
Litaker, Mark
Delirium is a common neuropsychiatric syndrome that occurs most frequently in older adults with dementia and is referred to as delirium superimposed on dementia (DSD). Our aim in this pilot project was to demonstrate that implementation of cognitively stimulating activities is clinically feasible and has potential to reduce delirium severity and duration and functional loss […]
A randomized clinical trial of theory-based activities for the behavioral symptoms of dementia in nursing home residents
Kolanowski, Ann,
Litaker, Mark,
Buettner, Lin,
Moeller, Joyel,
Costa, Paul T., Jr.
Objectives: To test the main and interactive effects of activities derived from the Need-Driven Dementia-Compromised Behavior model for responding to behavioral symptoms in nursing home residents.; Design: Randomized double-blind clinical trial.; Setting: Nine community-based nursing homes.; Participants: One hundred twenty-eight cognitively impaired residents randomly assigned to activities adjusted to functional level (FL) (n=32), personality style […]