This database contains 291 studies, archived under the term: "Behaviour"
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Galantamine (reminyl) in the treatment of severe Alzheimer’s disease
Twenty-five patients with Alzheimer’s disease (AD) in moderate-severe and severe stages received galantamine in dosage 8 mg daily during the 1st month with the following increasing to 16 mg daily. Six patients received 24 mg per day from the 3rd month. The total duration of therapy was 26 weeks. 15 patients received in addition the […]
Early-stage memory loss support groups: outcomes from a randomized controlled clinical trial
Logsdon, Rebecca G.,
Pike, Kenneth C.,
McCurry, Susan M.,
Hunter, Patricia,
Maher, Joanne,
Snyder, Lisa,
Teri, Linda
Objectives: This article describes results of a randomized controlled trial comparing a time-limited early-stage memory loss (ESML) support group program conducted by a local Alzheimer’s Association chapter to a wait-list (WL) control condition.; Methods: One hundred and forty-two dyads were randomized in blocks to ESML (n = 96) or WL (n = 46). Mean age […]
Levetiracetam: a practical option for seizure management in elderly patients with cognitive impairment
Lippa, Carol F.,
Rosso, Andrea,
Hepler, Marjorie,
Jenssen, Sigmund,
Pillai, Jyoti,
Irwin, David
Cognitive impairment and seizures are common in our aging population. Anticonvulsant treatment is problematic due to sedation, cognitive slowing, and behavioral changes. Levetiracetam has favorable pharmacokinetics, good efficacy in elderly individuals, a favorable side effect profile, and lacks major drug interactions. We conducted a prospective, uncontrolled, phase 4, open label, 12-week study of levetiracetam to […]
Technology-aided verbal instructions to help persons with mild or moderate Alzheimer’s disease perform daily activities
Lancioni, Giulio E.,
Singh, Nirbhay N.,
O’Reilly, Mark F.,
Sigafoos, Jeff,
Tatulli, Emanuela,
Rigante, Valeria,
Zonno, Nadia,
Perilli, Viviana,
Pinto, Katia,
Minervini, Mauro G.
These two studies extended previous research on the use of verbal instructions and support technology for helping persons with mild or moderate Alzheimer’s disease perform daily activities. Study I included seven participants who were to carry out one of two previously targeted activities (i.e., either coffee preparation or table setting). Study II included four participants […]
Treatment of behavioral and psychological symptoms of Alzheimer-type dementia with Yokukansan in clinical practice
Hayashi, Yoshihito,
Ishida, Yasushi,
Inoue, Teruhiko,
Udagawa, Mitsutaka,
Takeuchi, Kouzou,
Yoshimuta, Hirofumi,
Kiue, Kouichirou,
Ninomiya, Yoshimasa,
Kawano, Jiro,
Sameshima, Tetsuro,
Kawahara, Takashi,
Goto, Isamu,
Shudo, Kenji,
Kurayama, Shigeki,
Nakamura, Jungo,
Okahara, Kazunori,
Mitsuyama, Yoshio
The efficacy and safety of the kampo medicine Yokukansan (YKS, TJ-54) in the treatment of behavioral and psychological symptoms of dementia (BPSD) were investigated in patients with Alzheimer’s disease (AD) in an open-label study. This study included 26 patients who had been diagnosed as having AD and were not treated with donepezil hydrochloride. These patients […]
Low-dose divalproex in agitated patients with Alzheimer’s disease
Adequate treatment of behavioral disturbances in Alzheimer’s disease is both important and difficult. This report describes a case series that examined the effectiveness and safety of low-dose divalproex in the treatment of agitated patients with Alzheimer’s disease who were admitted to an inpatient geriatric psychiatry unit over a 1-year period. All patients had agitation due […]
Effects of exercise programs to prevent decline in health-related quality of life in highly deconditioned institutionalized elderly persons: a randomized controlled trial
Dechamps, Arnaud,
Diolez, Philippe,
Thiaudière, Eric,
Tulon, Aurore,
Onifade, Chérifa,
Vuong, Tuan,
Helmer, Catherine,
Bourdel-Marchasson, Isabelle
Background: Our objective was to assess the effects of targeted exercise programs on health-related quality of life compared with usual care based on the ability to perform activities of daily living (ADL) and the Neuropsychiatric Inventory scores in geriatric institutionalized persons.; Methods: A randomized controlled trial of 2 exercise programs vs usual care was conducted […]