This database contains 53 studies, archived under the term: "cognitive impairment."
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Tea Consumption and Cognitive Impairment: A Cross-Sectional Study among Chinese Elderly
Shen, Wei,
Xiao, Yuanyuan,
Ying, Xuhua,
Li, Songtao,
Zhai, Yujia,
Shang, Xiaopeng,
Li, Fudong,
Wang, Xinyi,
He, Fan,
Lin, Junfen
Background: Laboratorial and epidemiological researches suggested that tea exhibited potential neuroprotective effect which may prevent cognitive impairment, but there were few data among the elderly aged 60 years and above in China.; Objective: The objective was to explore the relationship between characteristics of tea consumption and cognitive impairment.; Design: We analyzed the baseline data from […]
Vitamins B₁₂, B₆, and folic acid for cognition in older men
Ford, A. H.,
Flicker, L.,
Alfonso, H.,
Thomas, J.,
Clarnette, R.,
Martins, R.,
Almeida, O. P.
[Correction Notice: An erratum for this article was reported in Vol 77(8) of Neurology (see record [rid]2011-21984-022[/rid]). In the original article, the daily dose of vitamin B12 used in the trial was reported as 400 μg, but it should have been 500 μg.] Objective: To investigate whether supplementing older men with vitamins B12, B6, and […]
The Computerized Self Test (CST): An interactive, internet accessible cognitive screening test for dementia
Dougherty, John H., Jr.,
Cannon, Rex L.,
Nicholas, Christopher R.,
Hall, Lorin,
Hare, Felicia,
Carr, Erika,
Dougherty, Andrew,
Janowitz, Jennifer,
Arunthamakun, Justin
The computer self test (CST) is an interactive, internet-based instrument designed to assess functional cognitive domains impaired by Alzheimer’s disease (AD) and mild cognitive impairment (MCI). This study consisted of 215 total subjects with a mean age of 75.24. The 84 cognitively impaired patients (excluding patients diagnosed as MCI) met all criteria set forth by […]
Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial
Cummings, J. L.,
Lyketsos, C. G.,
Peskind, E. R.,
Porsteinsson, A. P.,
Mintzer, J. E.,
Scharre, D. W.,
De La Gandara, J. E.,
Agronin, M.,
Davis, C. S.,
Nguyen, U.,
Shin, P.,
Tariot, P. N.,
Siffert, J.
IMPORTANCE: Agitation is common among patients with Alzheimer disease; safe, effective treatments are lacking. OBJECTIVE: To assess the efficacy, safety, and tolerability of dextromethorphan hydrobromide-quinidine sulfate for Alzheimer disease-related agitation. DESIGN, SETTING, AND PARTICIPANTS: Phase 2 randomized, multicenter, double-blind, placebo-controlled trial using a sequential parallel comparison design with 2 consecutive 5-week treatment stages conducted August […]
Use of anticholinergics and the risk of cognitive impairment in an African American population
Campbell, N. L.,
Boustani, M. A.,
Lane, K. A.,
Gao, S.,
Hendrie, H.,
Khan, B. A.,
Murrell, J. R.,
Unverzagt, F. W.,
Hake, A.,
Smith-Gamble, V.,
Hall, K.
Background: Anticholinergic properties of certain medications often go unrecognized, and are frequently used by the elderly population. Few studies have yet defined the long-term impact of these medications on the incidence of cognitive impairment. Methods: We report a 6-year longitudinal, observational study, evaluating 1,652 community-dwelling African American subjects over the age of 70 years who […]
Screening cognition in the elderly with metabolic syndrome
Viscogliosi, Giovanni,
Andreozzi, Paola,
Chiriac, Iulia Maria,
Cipriani, Elisa,
Servello, Adriana,
Ettorre, Evaristo,
Marigliano, Vincenzo
Background: Metabolic syndrome reaches its highest prevalence in the elderly, and evidence suggests that metabolic syndrome could be an independent risk factor for cognitive impairment. The aims of this study were to detect whether patients with metabolic syndrome have lower cognition and to investigate whether there is a relationship with cognition and single metabolic syndrome […]
Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: a 6-month randomised controlled trial
Sinn, Natalie,
Milte, Catherine M.,
Street, Steven J.,
Buckley, Jonathan D.,
Coates, Alison M.,
Petkov, John,
Howe, Peter R.C.
Depressive symptoms may increase the risk of progressing from mild cognitive impairment (MCI) to dementia. Consumption of n-3 PUFA may alleviate both cognitive decline and depression. The aim of the present study was to investigate the benefits of supplementing a diet with n-3 PUFA, DHA and EPA, for depressive symptoms, quality of life (QOL) and […]