This database contains 160 studies, archived under the term: "Background"
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Dementia care management: going new ways in ambulant dementia care within a GP-based randomized controlled intervention trial
Eichler, Tilly,
Thyrian, Jochen René,
Dreier, Adina,
Wucherer, Diana,
Kohler, Leonore,
Fiß, Thomas,
Böwing, Georgia,
Michalowsky, Bernhard,
Hoffmann, Wolfgang
Background: Increasing prevalence of dementia is a major challenge for the German healthcare system. The study DelpHi-MV (“Dementia: life- and person-centered help in Mecklenburg-Western Pomerania”) aims to implement and evaluate an innovative subsidiary support system for persons with dementia (PwDs) living at home and their caregivers.; Methods: DelpHi-MV is a GP-based cluster randomized controlled intervention […]
German adaptation of the Resources for Enhancing Alzheimer’s Caregiver Health II: study protocol of a single-centred, randomised controlled trial
Heinrich, Stephanie,
Berwig, Martin,
Simon, Anke,
Jänichen, Jenny,
Hallensleben, Nina,
Nickel, Witiko,
Hinz, Andreas,
Brähler, Elmar,
Gertz, Hermann-Josef
Background: Caring for a family member with dementia is extremely stressful, and contributes to psychiatric and physical illness among caregivers. Therefore, a comprehensive programme called Resources for Enhancing Alzheimer’s Caregiver Health II (REACH II) was developed in the United States to enhance the health of Alzheimer’s caregivers. REACH II causes a clear reduction of the […]
Early detection of memory impairment in people over 65 years old consulting at Health Examination Centers for the French health insurance: the EVATEM protocol
Vannier-Nitenberg, Christiane,
Dauphinot, Virginie,
Bongue, Bienvenu,
Sass, Catherine,
Rouch, Isabelle,
Beauchet, Olivier,
Krolak-Salmon, Pierre,
Fantino, Bruno
Background: Only half of those living with Alzheimer’s disease in France are currently diagnosed, and only one patient in three is supported during the early stages of dementia. This study aims to evaluate three cognitive tests for their predictive ability to diagnose mild cognitive impairments and Alzheimer’s disease and related disorders. For people aged 65 […]
Alzheimer’s disease–input of vitamin D with mEmantine assay (AD-IDEA trial): study protocol for a randomized controlled trial
Annweiler, Cedric,
Fantino, Bruno,
Parot-Schinkel, Elsa,
Thiery, Samuel,
Gautier, Jennifer,
Beauchet, Olivier
Background: Current treatments for Alzheimer’s disease and related disorders (ADRD) are symptomatic and can only temporarily slow down ADRD. Future possibilities of care rely on multi-target drugs therapies that address simultaneously several pathophysiological processes leading to neurodegeneration. We hypothesized that the combination of memantine with vitamin D could be neuroprotective in ADRD, thereby limiting neuronal […]
Exercise rehabilitation on home-dwelling patients with Alzheimer’s disease–a randomized, controlled trial. Study protocol
Pitkälä, Kaisu H.,
Raivio, Minna M.,
Laakkonen, Marja-Liisa,
Tilvis, Reijo S.,
Kautiainen, Hannu,
Strandberg, Timo E.
Background: Besides cognitive decline, Alzheimer’s disease (AD) leads to physical disability, need for help and permanent institutional care. The trials investigating effects of exercise rehabilitation on physical functioning of home-dwelling older dementia patients are still scarce. The aim of this study is to investigate the effectiveness of intensive exercise rehabilitation lasting for one year on […]
The Danish Alzheimer intervention study: rationale, study design and baseline characteristics of the cohort
WALDEMAR, G.,
Waldorff, F. B.,
Buss, D. V.,
Eckermann, A.,
Keiding, N.,
Rishøj, S.,
Siersma, V.,
Sørensen, J.,
Sørensen, L. V.,
VOGEL, A.
Background: There is a lack of appropriately designed trials investigating the efficacy of psychosocial interventions for patients with mild dementia and their family caregivers. This paper reports the rationale and design of the Danish Alzheimer Disease Intervention Study and baseline characteristics of the cohort.; Methods: The study was a 1-year multicentre randomized controlled rater-blinded trial […]
A study protocol to investigate the management of depression and challenging behaviors associated with dementia in aged care settings
McCabe, Marita P.,
Mellor, David,
Davison, Tanya E.,
Karantzas, Gery,
von Treuer, Kathryn,
O'Connor, Daniel W.
Background: The high occurrence and under-treatment of clinical depression and behavioral and psychological symptoms of dementia (BPSD) within aged care settings is concerning, yet training programs aimed at improving the detection and management of these problems have generally been ineffective. This article presents a study protocol to evaluate a training intervention for facility managers/registered nurses […]