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This database contains 71 studies, archived under the term: "APA"

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Efficacy and tolerability of Ginkgo biloba extract EGb 761® by type of dementia: Analyses of a randomised controlled trial
Secondary analyses of a randomised controlled trial were performed to find out whether treatment effects of Ginkgo biloba extract EGb 761® differed by type of dementia. Three hundred ninety-five patients aged 50 years or above, with dementia with neuropsychiatric features were treated with EGb 761® (240 mg/day) or placebo for 22 weeks. Patients scored between […]

Interaction effects of education and health status on cognitive change: A 6-year follow-up of the Maastricht Aging Study
Objectives: The aim of this study was to test for interactions between education and health status (i.e., physical, social, and psychological functioning) with respect to baseline cognitive performance and change over 6 years. Method: Longitudinal data from the Maastricht Aging Study of 1344 men and women aged 24-47 and 49-77 were used. Results: Education by […]

De invloed van Dementia Care Mapping (DCM) op moeilijk hanteerbaar gedrag van mensen met dementie en de arbeidstevredenheid van verzorgenden: Een pilotstudie. = The influence of Dementia Care Mapping (DCM) on behavioural problems of persons with dementia and the job satisfaction of caregivers: A pilot study
The prevalence of behavioural problems in nursing home residents with dementia is high. Knowledge based on practical experiences suggests that problems diminish when caregivers are better able to recognize and acknowledge the individual psychosocial needs of residents. Dementia Care Mapping (DCM) is a method designed to support caregivers in providing person centered care. After implementing […]

Ginkgo biloba prevention trials: More than an ounce of prevention learned
Objective: To determine effectiveness of G biloba vs placebo in reducing the incidence of all-cause dementia and Alzheimer disease (AD) in elderly individuals with normal cognition and those with mild cognitive impairment (MCI). Design, Setting, and Participants: Randomized, double-blind, placebo-controlled clinical trial conducted in 5 academic medical centers in the United States between 2000 and […]

Predictors of entering 24-h care for people with Alzheimer’s disease: Results from the LASER-AD study
Objectives: Many studies have investigated predictors of people with dementia entering 24-h care but this is the first to consider a comprehensive range of carer and care recipient (CR) characteristics derived from a systematic review, in a longitudinal cohort study followed up for several years. Methods: We interviewed 224 people with Alzheimer’s disease (AD) and […]

Musical structural determinants of emotional judgments in dementia of the Alzheimer type
People with dementia of the Alzheimer type (DAT) may well be emotionally soothed by listening to music. However, very few systematic studies have been conducted to support the anecdotal evidence. DAT does damage certain cerebral structures that subsume emotional processing, and some studies have demonstrated deficits affecting emotional judgments of facial expression and prosody in […]

Impact of TimeSlips, a creative expression intervention program, on nursing home residents with dementia and their caregivers
Purpose: Creative expression (CE) programs are emerging interventions to improve the quality of care and life of persons with dementia (PWDs) in long-term care settings. However, limited empirical evidence exists to support the effectiveness of these programs. Here, we report the findings from an assessment of the impact of TimeSlips (TS), a group storytelling program […]

Treatment of vascular risk factors is associated with slower decline in Alzheimer disease
Background: There is growing evidence that vascular risk factors (VRF) contribute to cognitive decline. Whether their treatment can slow down the progression of Alzheimer disease (AD) remains unsettled. The aim of this observational study was to evaluate whether the treatment of VRF is associated with a slower cognitive decline in patients who have AD without […]

Managing agitated behaviour in people with Alzheimer’s disease: The role of live music
Background: Agitation due to Alzheimer’s disease (AD) presents a challenge to occupational therapists working in the older people care sector. Recently background music and music therapy have emerged as promising tools in the management of agitation in AD. This exploratory study investigated whether live music could reduce agitated behaviour in people with AD. Method: A […]

Goal-oriented cognitive rehabilitation for an individual with mild cognitive impairment: Behavioural and neuroimaging outcomes
An individual, goal-oriented cognitive rehabilitation intervention was conducted with AB, a 77-year-old woman with MCI. Outcomes were evaluated using a client-centred measure of goal achievement and an experimental associative learning task testing a skill practised in the intervention. Pre- and post-intervention fMRI scans were compared to examine changes in brain activation. Following intervention, AB showed […]

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