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Goal-oriented cognitive rehabilitation for an individual with mild cognitive impairment: Behavioural and neuroimaging outcomes


Clare, Linda, van Paasschen, Jorien, Evans, Suzannah J., Parkinson, Caroline, Woods, Robert T, Linden, David E. J.


Neurocase, Volume: 15, No.: 4, Pages.: 318-331

Year of Publication



An individual, goal-oriented cognitive rehabilitation intervention was conducted with AB, a 77-year-old woman with MCI. Outcomes were evaluated using a client-centred measure of goal achievement and an experimental associative learning task testing a skill practised in the intervention. Pre- and post-intervention fMRI scans were compared to examine changes in brain activation. Following intervention, AB showed improved performance on rehabilitation goals and on the associative learning task. There were significant decreases in brain activation in sensory areas and significant increases in memory-related areas. Both client-centred measures and fMRI may assist in detecting clinically-meaningful changes resulting from cognitive rehabilitation interventions. (PsycINFO Database Record (c) 2012 APA, all rights reserved). (journal abstract)

Bibtex Citation

@article{Clare_2009, doi = {10.1080/13554790902783116}, url = {}, year = 2009, month = {jul}, publisher = {Informa {UK} Limited}, volume = {15}, number = {4}, pages = {318--331}, author = {Linda Clare and Jorien van Paasschen and Suzannah J. Evans and Caroline Parkinson and Robert T. Woods and David E. J. Linden}, title = {Goal-oriented cognitive rehabilitation for an individual with Mild Cognitive Impairment: Behavioural and neuroimaging outcomes}, journal = {Neurocase} }


an, cognitive, cognitive impairment, cognitive rehabilitation, fmri, functional magnetic resonance imaging, goal setting, goaloriented, individual, intervention, memory, mild cognitive impairment, rehabilitation

Countries of Study


Types of Dementia

Mild Cognitive Impairment (MCI)

Types of Study

Before and After Study

Type of Outcomes

ADLs/IADLs, Cognition

Type of Interventions

Non-pharmacological Treatment

Non-Pharmaceutical Interventions

Behavioural Therapies