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Your search has found 227 articles in the database for the term 'Quality of Life (self-rated)'

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A randomized, double-blind, placebo-controlled trial of memantine in a behaviorally enriched sample of patients with moderate-to-severe Alzheimer’s disease

...Background: Agitation and aggression in Alzheimer’s disease (AD) are amongst the most serious of neuropsychiatric symptoms, and contribute to poor outcomes and worse quality of life. Previous studies have...

The effect of an aloe polymannose multinutrient complex on cognitive and immune functioning in Alzheimer’s disease

...Alzheimer’s disease (AD) is a leading killer of Americans, imparts a significant toll on the quality of life of the patient and primary caregiver, and results in inordinate costs...

Optimal blood pressure for cognitive function: findings from an elderly African-American cohort study

...cognitive function has been identified, which may provide useful clinical information on optimal BP control in cognitive health and lead to better quality of life for elderly adults.; © 2013,...

Cost effectiveness of donepezil in the treatment of mild to moderate Alzheimer’s disease: A UK evaluation using discrete-event simulation

Background: Recommendations in the UK suggest restricting treatment of Alzheimer’s disease with cholinesterase inhibitors, on cost-effectiveness grounds, to patients with moderate cognitive decline. As the economic analyses that...

Clinical outcomes and complications of enteral nutrition among older adults

...displacement is frequent with NGT but not with PEG and may be a cause of physical restraint, compromising in this way patient’s quality of life. In this study, survival was...

Lipid lowering agents, cognitive decline, and dementia: the three-city study

...study, adjusting for multiple confounders, found no evidence that LLA given in late life reduced the risk of cognitive decline and dementia, but did raise the possibility that women with...

Risk of incident dementia in drug-untreated arterial hypertension: a population-based study

...Arterial hypertension in midlife may increase the risk of late-life dementia. Notably, there is conflicting data as to whether hypertension in the elderly (age 65 years and older) is...

The burden of spousal caregiving: a preliminary psychometric evaluation of the German version of the Zarit burden interview

...to strong correlations with caregiver life satisfaction and depression, as well as patients’ dependency, neuropsychiatric symptoms, and dementia severity.; Conclusion: The psychometric qualities of the G-ZBI indicate that it is...

The effect of midlife physical activity on structural brain changes in the elderly

...the GM density localized mainly in frontal lobes. There was no significant association between midlife physical activity and severe WML later in life after full adjustments (OR 4.20, 95% CI...

Evidence for neurocognitive plasticity in at-risk older adults: the experience corps program

...These pilot results provide proof of concept for use-dependent brain plasticity in later life, and, that interventions designed to promote health and function through everyday activity may enhance plasticity in...

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