Bokde, Arun L. W., Karmann, Michaela, Teipel, Stefan J., Born, Christine, Lieb, Martin, Reiser, Maximilian F., Möller, Hans-Jürgen, Hampel, Harald

Visual perception has been shown to be altered in Alzheimer disease (AD) patients, and it is associated with decreased cognitive function. Galantamine is an active cholinergic agent, which has been shown to lead to improved cognition in mild to moderate AD patients. This study examined brain activation in a group of mild AD patients after […]

Kurita, Akira, Murakami, Maiko, Takagi, Satoshi, Matsushima, Masato, Suzuki, Masahiko

Visual hallucinations (VHs) are common in dementia with Lewy bodies (DLB) and Parkinson’s disease with dementia (PDD), while auditory hallucinations are rare. To neurophysiologically investigate the pathophysiology of VHs in these disorders, we studied event-related potentials (ERPs) of DLB, PDD, and Alzheimer’s disease (AD) patients. We compared visual and auditory ERP latencies among PDD patients […]

Daiello, Lori A., Ott, Brian R., Festa, Elena K., Friedman, Michael, Miller, Lindsay A., Heindel, William C.

Objective: We conducted a combined observational cohort and case-control study in patients with Alzheimer disease (AD) to assess the effects of acetylcholinesterase inhibitor (ChEI) treatment on cognitive functions important for driving.; Methods: Performance of 24 outpatients with newly diagnosed (untreated) early-stage AD was compared before beginning ChEI (pre-ChEI) and after 3 months of therapy (post-ChEI) […]

Weijenberg, Roxane Anthea Francesca, Lobbezoo, Frank, Knol, Dirk Lucas, Tomassen, Jori, Scherder, Erik Johan Anton

Background: Worldwide, millions of people are suffering from dementia and this number is rising. An index of quality of life (QoL) can describe the impact a disease or treatment has on a person’s wellbeing. QoL comprises many variables, including physical health and function, and mental health and function. QoL is related to masticatory ability and […]

Pyo, Geunyeong, Ala, Tom, Kyrouac, Gregory A., Verhulst, Steven J.

Objective assessment of memory functioning is an important part of evaluation for Dementia of Alzheimer Type (DAT). The revised Picture Recognition Memory Test (r-PRMT) is a test for visual recognition memory to assess memory functioning of persons with intellectual disabilities (ID), specifically targeting moderate to severe ID. A pilot study was performed to investigate whether […]

Goudour, Amandine, Samson, Séverine, Bakchine, Serge, Ehrlé, Nathalie

The purpose of this study was to assess the effects of semantic stimulation of Alzheimer’s patients on semantic memory comparatively to psychological support. We conducted semantic training with two target categories (musical instruments and human actions), because these concepts were massively failed in previous data collected in Alzheimer’s disease. Ten patients (57-78 year old, MMSE […]

De Anna, Francesca, Felician, Olivier, Barbeau, Emmanuel, Mancini, Julien, Didic, Mira, Ceccaldi, Mathieu

Objective: This study aims to evaluate whether assessing memory using the visual recognition memory task DMS48 in amnestic mild cognitive impairment (aMCI) can contribute to the early diagnosis of Alzheimer’s disease (AD). In an 18-month follow-up study, we assessed if longitudinal change in aMCI patients who failed on the DMS48 differs from that of patients […]