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This database contains 1041 studies, archived under the term: "male"

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Cognitive assessment of elderly patients in the emergency department: a comparison between standard tools, medical records and physicians’ perception

Introduction: We evaluated the accuracy of physician recognition of cognitive impairment in elderly patients in emergency departments (ED). In particular, we evaluated the accuracy of the subjective impression of the physician on patients’ cognition (a comparison of the information obtained from the responsible physician with the S-IQCODE, a cognitive impairment screening test), and the accuracy […]

Ear therapy and massage therapy in the elderly with dementia: a pilot study

Objective: To assess the impact of massage versus ear acupuncture on behavior and participation in occupational therapy of dementia patients.; Methods: We performed a controlled, randomized longitudinal trial approved by the Bioethics Commission of the University of Extremadura. One hundred twenty elderly subjects with dementia institutionalized in residential homes in Extremadura (Spain) received treatment based […]

Cognitive change in donepezil treated patients with vascular or mixed dementia

Background: vascular dementia (VaD) and mixed Alzheimer’s disease (AD/VaD) are common. How best to monitor treatment is not clear. Our objective was to compare responsiveness and construct validity of change scores, following donepezil treatment, of the standardized Mini-Mental State Examination (sMMSE) and other measures potentially usable in primary care.; Methods: A six-month, outcome measurement study. […]

A randomized controlled trial of an activity specific exercise program for individuals with Alzheimer disease in long-term care settings

Objective: To determine whether an activity specific exercise program could improve ability to perform basic mobility activities in long-term care residents with Alzheimer disease (AD).; Design: Randomized, controlled, single-blinded clinical trial.; Setting: Residents of 7 long-term care facilities.; Participants: Eighty-two long-term care residents with mild to severe AD.; Intervention: An activity specific exercise program was […]

Patterns of cognitive decline, conversion rates, and predictive validity for 3 models of MCI

Our objective was to compare the predictive ability of different models of mild cognitive impairment (MCI) as a marker of incipient dementia in a longitudinal population-based Canadian sample. We examined the use of existing, well-documented MCI criteria using data from persons who underwent a clinical examination in the second wave of the Canadian Study of […]

Prospective flutemetamol positron emission tomography and histopathology in normal pressure hydrocephalus

Unlabelled: BACKGOUND/OBJECTIVE: To determine the level of association between uptake of the amyloid positron emission tomography (PET) imaging agent [(18)F]flutemetamol and the level of amyloid-β measured by immunohistochemical and histochemical staining in a frontal cortical region biopsy site.; Methods: Seventeen patients with probable normal pressure hydrocephalus (NPH) underwent prospective [(18)F]flutemetamol PET and subsequent frontal cortical […]

Individual music therapy for agitation in dementia: an exploratory randomized controlled trial

Objectives: Agitation in nursing home residents with dementia leads to increase in psychotropic medication, decrease in quality of life, and to patient distress and caregiver burden. Music therapy has previously been found effective in treatment of agitation in dementia care but studies have been methodologically insufficient. The aim of this study was to examine the […]

Prevalence of psychotropic medication use among German and Austrian nursing home residents: a comparison of 3 cohorts

Background: Despite increasing knowledge about the limited effectiveness and severe adverse effects, the prescription rate of psychotropic medications in frail elderly persons remains high. Prescriptions are mainly made to control behavioral and psychological symptoms of dementia, although factors associated with prescriptions are rarely reported. However, such information is a prerequisite to develop intervention programs aiming […]

Galantamine treatment in outpatients with mild Alzheimer’s disease

Objective: To assess long-term effectiveness of galantamine in community-dwelling persons with mild Alzheimer’s disease.; Methods: Prospective open-label trial including patients with mild AD (NINCDS-ADRDA criteria) treated with galantamine for up to 36 months. Outcome parameters included ADAS-cog/11, Bayer-ADL scale (self- and caregivers’ ratings), 10-item NPI and CGI-change, safety and tolerability measures. Data are presented based […]

Vital conversations with family in the nursing home: preparation for end-stage dementia care

Family members of persons with advanced dementia may be asked to make complex treatment decisions without having adequate knowledge regarding the risks and benefits. This 6-month, prospective, randomized trial tested the effect of an intervention consisting of a face-to-face, structured conversation about end-of-life care options with family members of nursing home residents with advanced dementia. […]

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