This database contains 1063 studies, archived under the term: "female"
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Comparisons of plasma/serum micronutrients between Okinawan and Oregonian elders: a pilot study
Dodge, Hiroko H.,
Katsumata, Yuriko,
Todoriki, Hidemi,
Yasura, Shoutoku,
Willcox, D. Craig,
Bowman, Gene L.,
Willcox, Bradley,
Leonard, Scott,
Clemons, Aaron,
Oken, Barry S.,
Kaye, Jeffrey A.,
Traber, Maret G.
Certain micronutrients are protective against cognitive decline. We examined whether there is any uniform pattern of circulating micronutrients cross-culturally that are associated with successful cognitive aging. For the U.S. sample, we used the stored serum/plasma of 115 participants, collected in Oregon, USA. The Okinawa sample consisted of 49 participants selected using similar inclusion criteria as […]
The association of statin use and statin type and cognitive performance: analysis of the reasons for geographic and racial differences in stroke (REGARDS) study
Glasser, Stephen P.,
Wadley, Virginia,
Judd, Suzanne,
Kana, Bhumika,
Prince, Valerie,
Jenny, Nancy,
Kissela, Brett,
Safford, Monika,
Prineas, Ronald,
Howard, George
Background: Statin use and type have been variably associated with impaired or improved cognitive performance.; Hypothesis: To assess the association of statin use and type (lipophilic vs hydrophilic) and cognitive impairment.; Methods: Cross-sectional analysis of 24 595 participants (7191 statin users and 17 404 nonusers) age > or = 45 years, from a population-based national […]
Treating neuropsychiatric symptoms in dementia with Lewy bodies: a randomized controlled-trial
Culo, Sandi,
Mulsant, Benoit H.,
Rosen, Jules,
Mazumdar, Sati,
Blakesley, Richard E.,
Houck, Patricia R.,
Pollock, Bruce G.
Sensitivity to psychotropic medications presents a therapeutic challenge when treating neuropsychiatric symptoms in patients with dementia with Lewy bodies (DLB). We compared under randomized, double-blinded conditions the tolerability and efficacy of citalopram and risperidone in the treatment of behavioral and psychotic symptoms in patients with DLB and Alzheimer disease (AD). Thirty-one participants with DLB and […]
Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: the AIBL Active trial
Cyarto, Elizabeth V.,
Lautenschlager, Nicola T.,
Desmond, Patricia M.,
Ames, David,
Szoeke, Cassandra,
Salvado, Olivier,
Sharman, Matthew J.,
Ellis, Kathryn A.,
Phal, Pramit M.,
Masters, Colin L.,
Rowe, Christopher C.,
Martins, Ralph N.,
Cox, Kay L.
Background: Older adults free of dementia but with subjective memory complaints (SMC) or mild cognitive impairment (MCI) are considered at increased risk of cognitive decline. Vascular risk factors (VRF), including hypertension, heart disease, smoking, hypercholesterolemia and lack of physical activity (PA) have been identified as modifiable risk factors contributing to cognitive decline, and white matter […]
Can a tailored exercise and home hazard reduction program reduce the rate of falls in community dwelling older people with cognitive impairment: protocol paper for the i-FOCIS randomised controlled trial
Close, Jacqueline C. T.,
Wesson, Jacqueline,
Sherrington, Catherine,
Hill, Keith D.,
Kurrle, Sue,
Lord, Stephen R.,
Brodaty, Henry,
Howard, Kirsten,
Gitlin, Laura N,
O'Rourke, Sandra D.,
Clemson, Lindy
Background: The rate of falls in community dwelling older people with cognitive impairment (CI) is twice that of a cognitively intact population, with almost two thirds of people with CI falling annually. Studies indicate that exercise involving balance and/or a home hazard reduction program are effective in preventing falls in cognitively intact older people. However […]
Longer duration of hormonal contraceptive use predicts better cognitive outcomes later in life
Background: The cognitive effects of postmenopausal hormone therapy (HT) have been studied extensively, but little is known about the relationship between premenopausal hormone use and cognition. Hormonal contraceptive use vs. nonuse may be a potential factor influencing cognitive processes in midlife. The aim of this study is to explore the effect of modification of hormone […]
Public-private partnerships improve health outcomes in individuals with early stage Alzheimer’s disease
Purpose: In a collaborative effort between the Missouri Department of Health, Area Agencies on Aging (AAA), Alzheimer Association, and academic researchers, we tested whether early dementia detection and comprehensive care consultations would improve health outcomes in care receivers (CRs) and their family caregivers (FCGs), therefore addressing an important public health concern.; Participants and Methods: A […]
Preserving Identity and Planning for Advance Care (PIPAC): preliminary outcomes from a patient-centered intervention for individuals with mild dementia
Hilgeman, Michelle M.,
Allen, Rebecca S.,
Snow, A. Lynn,
Durkin, Daniel W.,
DeCoster, Jamie,
Burgio, Louis D.
Objectives: The purpose of this pilot study was to conduct limited-efficacy testing of the newly developed Preserving Identity and Planning for Advance Care (PIPAC) intervention on self-reported and proxy-reported emotional and health-related outcomes of individuals in the early stages of dementia.; Method: A two-group comparison design was implemented. Blocked randomization was used to assign individuals […]