This database contains 19 studies, archived under the term: "Epidemiological"
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Statins and serum cholesterol’s associations with incident dementia and mild cognitive impairment
Beydoun, May A.,
Beason-Held, Lori L.,
Kitner-Triolo, Melissa H.,
Beydoun, Hind A.,
Ferrucci, Luigi,
Resnick, Susan M.,
Zonderman, Alan B.
Background: Statin use and serum cholesterol reduction have been proposed as preventions for dementia and mild cognitive impairment (MCI). Methods: 1604 and 1345 eligible participants from the Baltimore Longitudinal Study of Aging (BLSA) were followed after age 50 for a median time of around 25 years, to examine the incidence of dementia (n = 259) […]
Mild to moderate cognitive impairment is a major risk factor for mortality and nursing home admission in the first year after hip fracture
Schaller, F.,
Sidelnikov, E.,
Theiler, R.,
Egli, A.,
Staehelin, H. B.,
Dick, W.,
Dawson-Hughes, B.,
Grob, D.,
Platz, A.,
Can, U.,
Bischoff-Ferrari, H. A.
Background: It is not well established if and to what extent mild to moderate cognitive impairment predicts mortality and risk of nursing home admission after hip fracture.; Objective: To investigate prospectively whether and to what extent mild to moderate cognitive impairment, contributes to mortality and admission to nursing home in the first year after acute […]
Wavelet coherence model for diagnosis of Alzheimer disease
This article presents a wavelet coherence investigation of electroencephalograph (EEG) readings acquired from patients with Alzheimer disease (AD) and healthy controls. Pairwise electrode wavelet coherence is calculated over each frequency band (delta, theta, alpha, and beta). For comparing the synchronization fraction of 2 EEG signals, a wavelet coherence fraction is proposed which is defined as […]
Hormone levels and cognitive function in postmenopausal midlife women
Ryan, Joanne,
Stanczyk, Frank Z.,
Dennerstein, Lorraine,
Mack, Wendy J.,
Clark, Margaret S.,
Szoeke, Cassandra,
Kildea, Daniel,
Henderson, Victor W.
Gonadal hormones may influence cognitive function. Postmenopausal midlife women in the population-based Melbourne Women’s Midlife Health Project cohort were administered a comprehensive battery of neuropsychological tests on two occasions 2 years apart. Participants (n = 148, mean age 60 years) had undergone natural menopause and were not using hormone therapy. Estrone, total and free estradiol, […]
Being overweight in midlife is associated with lower cognitive ability and steeper cognitive decline in late life
Dahl, Anna,
Hassing, Linda B.,
Fransson, Eleonor,
Berg, Stig,
Gatz, Margaret,
Reynolds, Chandra A.,
Pedersen, Nancy L.
Background: Although an increasing body of evidence links being overweight in midlife with an increased risk for dementia in late life, no studies have examined the association between being overweight in midlife and cognitive ability in late life. Our aim was to examine the association between being overweight in midlife as measured by body mass […]
A prospective analysis of elevated fasting glucose levels and cognitive function in older people: results from PROSPER and the Rotterdam Study
Euser, Sjoerd M.,
Sattar, Naveed,
Witteman, Jacqueline C. M.,
Bollen, Eduard L. E. M.,
Sijbrands, Eric J. G.,
Hofman, Albert,
Perry, Ivan J.,
Breteler, Monique M. B.,
Westendorp, Rudi G.J.
Objective: To investigate the relationship between fasting glucose levels, insulin resistance, and cognitive impairment in old age. Diabetes is associated with cognitive impairment in older people. However, the link between elevated fasting glucose levels and insulin resistance in nondiabetic individuals, and the risk of cognitive impairment is unclear.; Research Design and Methods: We analyzed data […]
Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis
Peters, Ruth,
Beckett, Nigel,
Forette, Francoise,
Tuomilehto, Jaakko,
Ritchie, Craig,
Walton, Ivan,
Waldman, Adam,
Clarke, Robert,
Poulter, Ruth,
Fletcher, Astrid,
Bulpitt, Christopher
Background: It is well known that the global population is aging and that those over the age of 80 are the fastest growing part of this expansion. Also known is that prevalence of hypertension and cognitive decline both increase with increasing age.; Method: The Hypertension in the Very Elderly Trial (HYVET) was a double blind […]
Visual evoked potentials to pattern, motion and cognitive stimuli in Alzheimer’s disease
Kubová, Z.,
Kremlácek, J.,
Valis, M.,
Langrová, J.,
Szanyi, J.,
Vít, F.,
Kuba, M.
The aim of our study was to verify reported visual dysfunctions of patients with Alzheimer disease with the use of several variants of VEPs and visual ERPs and to learn whether these methods can be useful in diagnostics of AD. We tested 15 patients (6 women and 9 men, aged from 58 to 87) with […]
Midlife alcohol consumption and later risk of cognitive impairment: a twin follow-up study
Virtaa, Jyri J.,
Järvenpää, Tarja,
Heikkilä, Kauko,
Perola, Markus,
Koskenvuo, Markku,
Räihä, Ismo,
Rinne, Juha O.,
Kaprio, Jaakko
In this prospective follow-up study, we monitored the effects of midlife alcohol consumption and drinking patterns on cognitive impairment risks in late life. 1,486 subjects recruited from the Finnish Twin Cohort were included in the analyses. Alcohol consumption data was obtained with structured questionnaires in 1975 and 1981, and subjects were contacted between 1999 and […]