This database contains 231 studies, archived under the term: "ADLs/IADLs"
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Safety/Tolerability and efficacy of rivastigmine in taiwanese patients with Alzheimer’s disease: a prospective post-marketing surveillance study
Chiu, Pai-Yi,
Dai, Dao-En,
Hsu, Hai-Pei,
Lee, Chao,
Lin, Juei-Jueng,
Kuo, Hung-Chou,
Huang, Ying-Chih,
Liu, Yung-Chang,
Tsai, Ching-Piao
Background and Objectives: Rivastigmine is approved for the symptomatic treatment of mild to moderate dementia in patients with Alzheimer’s disease. The drug was launched in Taiwan in 2000. The primary objective of this post-marketing surveillance (PMS) study was to describe the safety/tolerability of treatment with rivastigmine capsules in patients with Alzheimer’s disease. The secondary objectives […]
Vitamin E and memantine in Alzheimer’s disease: clinical trial methods and baseline data
Dysken, Maurice W.,
Guarino, Peter D.,
Vertrees, Julia E.,
Asthana, Sanjay,
Sano, Mary,
Llorente, Maria,
Pallaki, Muralidhar,
Love, Susan,
Schellenberg, Gerard D.,
McCarten, J. Riley,
Malphurs, Julie,
Prieto, Susana,
Chen, Peijun,
Loreck, David J.,
Carney, Sara,
Trapp, George,
Bakshi, Rajbir S.,
Mintzer, Jacobo E.,
Heidebrink, Judith L.,
Vidal-Cardona, Ana,
Arroyo, Lillian M.,
Cruz, Angel R.,
Kowall, Neil W.,
Chopra, Mohit P.,
Craft, Suzanne,
Thielke, Stephen,
Turvey, Carolyn L.,
Woodman, Catherine,
Monnell, Kimberly A.,
Gordon, Kimberly,
Tomaska, Julie,
Vatassery, Govind
Background: Alzheimer’s disease (AD) has been associated with both oxidative stress and excessive glutamate activity. A clinical trial was designed to compare the effectiveness of (i) alpha-tocopherol, a vitamin E antioxidant; (ii) memantine (Namenda), an N-methyl-D-aspartate antagonist; (iii) their combination; and (iv) placebo in delaying clinical progression in AD.; Methods: The Veterans Affairs Cooperative Studies […]
Maintenance Cognitive Stimulation Therapy (CST) for dementia: a single-blind, multi-centre, randomized controlled trial of Maintenance CST vs. CST for dementia
Aguirre, Elisa,
Spector, Aimee,
Hoe, Juanita,
Russell, Ian T.,
Knapp, Martin,
Woods, Robert T,
Orrell, Martin
Background: Psychological treatments for dementia are widely used in the UK and internationally, but only rarely have they been standardised, adequately evaluated or systematically implemented. There is increasing recognition that psychosocial interventions may have similar levels of effectiveness to medication, and both can be used in combination. Cognitive Stimulation Therapy (CST) is a 7-week cognitive-based […]
Self-management in early-stage dementia: a pilot randomised controlled trial of the efficacy and cost-effectiveness of a self-management group intervention (the SMART study)
Quinn, Catherine,
Anderson, Daniel,
Toms, Gill,
Whitaker, Rhiannon,
Edwards, Rhiannon Tudor,
Jones, Carys,
Clare, Linda
Background: The possibility of living well with a long-term condition has been identified as centrally relevant to the needs of people living with dementia. Growing numbers of people with early-stage dementia are contributing accounts that emphasise the benefits of actively engaging in managing the condition. Self-management interventions share the common objectives of educating about the […]
Improving psychotropic drug prescription in nursing home patients with dementia: design of a cluster randomized controlled trial
Smeets, Claudia H. W.,
Smalbrugge, Martin,
Gerritsen, Debby L,
Nelissen-Vrancken, Marjorie H. J. M. G.,
Wetzels, Roland B.,
van der Spek, Klaas,
Zuidema, Sytse U.,
Koopmans, Raymond T. C. M.
Background: Neuropsychiatric symptoms are highly prevalent in nursing home patients with dementia. Despite modest effectiveness and considerable side effects, psychotropic drugs are frequently prescribed for these neuropsychiatric symptoms. This raises questions whether psychotropic drugs are appropriately prescribed. The aim of the PROPER (PRescription Optimization of Psychotropic drugs in Elderly nuRsing home patients with dementia) II […]
Implementatie, effecten en kosten van casemanagement voor mensen met dementie en hun mantelzorgers: Beschrijving van de COMPAS studie. = Comparing case management care models for people with dementia and their caregivers: The design of the COMPAS study
van Hout, H. P. J.,
Macneil Vroomen, J. L.,
Van Mierlo, L. D.,
Meiland, F. J. M.,
Moll van Charante, E. P.,
Joling, K. J.,
van den Dungen, P.,
Dröes, R. M.,
van der Horst, H. E.,
de Rooij, S. E. J. A.
Background: Dementia care in The Netherlands is shifting from fragmented, ad hoc care to more coordinated and personalized care. Case management contributes to this shift. The linkage model and a combination of intensive case management and joint agency care models were selected based on their emerging prominence in The Netherlands. It is unclear if these […]
Comparing Dutch case management care models for people with dementia and their caregivers: The design of the COMPAS study.
MacNeil Vroomen, Janet,
Van Mierlo, Lisa D.,
van de Ven, Peter M.,
Bosmans, Judith E,
van den Dungen, Pim,
Meiland, Franka J. M.,
Dröes, Rose-Marie,
Moll van Charante, Eric P.,
van der Horst, Henriëtte E,
de Rooij, Sophia E.,
van Hout, Hein P.J.
Background: Dementia care in the Netherlands is shifting from fragmented, ad hoc care to more coordinated and personalised care. Case management contributes to this shift. The linkage model and a combination of intensive case management and joint agency care models were selected based on their emerging prominence in the Netherlands. It is unclear if these […]