This database contains 530 studies, archived under the term: "Dementia (general / unspecified)"
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The effect of midlife physical activity on structural brain changes in the elderly
Rovio, Suvi,
Spulber, Gabriela,
Nieminen, Lasse J.,
Niskanen, Eini,
Winblad, Bengt,
Tuomilehto, Jaakko,
Nissinen, Aulikki,
Soininen, Hilkka,
Kivipelto, Miia
Physical activity has been associated with decreased dementia risk in recent studies, but the effects for structural brain changes (i.e. white matter lesions (WML) and/or brain atrophy) have remained unclear. The CAIDE participants were a random population-based sample studied in midlife and re-examined on average 21 years later (n=2000). A subpopulation (n=75; 31 control, 23 […]
Malnutrition in community-dwelling adults with dementia (NutriAlz Trial)
Objectives: The objective of this study is to assess the nutritional status, measured by the MNA, in community-dwelling elderly individuals with dementia and to identify clinical risk factors for nutritional risk or malnutrition.; Design: Cross-sectional analysis of a cluster randomized clinical trial (Nutrialz).; Setting: Community-dwelling individuals attending dementia clinics.; Participants: 940 individuals.; Measurements: The clinical […]
Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial
Romeo, R.,
Knapp, M.,
Hellier, J.,
Dewey, M.,
Ballard, C.,
Baldwin, R.,
Bentham, P.,
Burns, A.,
Fox, C.,
Holmes, C.,
Katona, C.,
Lawton, C.,
Lindesay, J.,
Livingston, G.,
McCrae, N.,
Moniz-Cook, E.,
Murray, J.,
Nurock, S.,
O'Brien, J.,
Poppe, M.,
Thomas, A.,
Walwyn, R.,
Wilson, K.,
Banerjee, S.
Background: Depression is a common and costly comorbidity in dementia. There are very few data on the cost-effectiveness of antidepressants for depression in dementia and their effects on carer outcomes.; Aims: To evaluate the cost-effectiveness of sertraline and mirtazapine compared with placebo for depression in dementia.; Method: A pragmatic, multicentre, randomised placebo-controlled trial with a […]
Psychotropic drug consumption at admission and discharge of nursing home residents
Rolland, Yves,
Andrieu, Sandrine,
Crochard, Anne,
Goni, Sylvia,
Hein, Christophe,
Vellas, Bruno
Objectives: To quantify transitions of residents into or out of nursing homes (NHs) and to describe psychotropic drug prescription at admission and discharge and with regard to dementia diagnosis.; Design: A descriptive, cross-sectional, noninterventional study.; Setting: The setting included 300 NH in France.; Participants: Participants included 2231 NH residents.; Measurements: Participants reported the number, origin, […]
Effects of a psychological intervention in a primary health care center for caregivers of dependent relatives: a randomized trial
Rodriguez-Sanchez, E.,
Patino-Alonso, M. C.,
Mora-Simon, S.,
Gomez-Marcos, M. A.,
Perez-Penaranda, A.,
Losada-Baltar, A.,
Garcia-Ortiz, L.
Purpose: To assess, in the context of Primary Health Care (PHC), the effect of a psychological intervention in mental health among caregivers (CGs) of dependent relatives.; Design and Methods: Randomized multicenter, controlled clinical trial. The 125 CGs included in the trial were receiving health care in PHC.; Inclusion Criteria: Identifying oneself as principal CG of […]
Physical activity program for patients with dementia and their relative caregivers: randomized clinical trial in Primary Health Care (AFISDEMyF study)
Rodriguez-Sánchez, Emiliano,
Criado-Gutiérrez, José,
Mora-Simón, Sara,
Muriel-Diaz, M,
Gómez-Marcos, Manuel A,
Recio-Rodríguez, José I,
Patino-Alonso, M,
Valero-Juan, Luis F,
Maderuelo-Fernandez, José A,
García-Ortiz, Luis
Background: The aging of the population has led to the increase of chronic diseases, especially dementia and cardiovascular diseases, and it has become necessary for their relatives to dedicate more time in caregiving.The objective in the first phase of this study is to evaluate the effectiveness of a Primary Health Care procedure to increase the […]
Ear therapy and massage therapy in the elderly with dementia: a pilot study
Rodríguez-Mansilla, Juan,
González-López-Arza, María Victoria,
Varela-Donoso, Enrique,
Montanero-Fernández, Jesús,
Jiménez-Palomares, María,
Garrido-Ardila, Elisa Maria
Objective: To assess the impact of massage versus ear acupuncture on behavior and participation in occupational therapy of dementia patients.; Methods: We performed a controlled, randomized longitudinal trial approved by the Bioethics Commission of the University of Extremadura. One hundred twenty elderly subjects with dementia institutionalized in residential homes in Extremadura (Spain) received treatment based […]