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Physical activity program for patients with dementia and their relative caregivers: randomized clinical trial in Primary Health Care (AFISDEMyF study)


Rodriguez-Sánchez, Emiliano, Criado-Gutiérrez, José, Mora-Simón, Sara, Muriel-Diaz, M, Gómez-Marcos, Manuel A, Recio-Rodríguez, José I, Patino-Alonso, M, Valero-Juan, Luis F, Maderuelo-Fernandez, José A, García-Ortiz, Luis


BMC Neurology, Volume: 14, Pages.: 63-63

Year of Publication



Background: The aging of the population has led to the increase of chronic diseases, especially dementia and cardiovascular diseases, and it has become necessary for their relatives to dedicate more time in caregiving.The objective in the first phase of this study is to evaluate the effectiveness of a Primary Health Care procedure to increase the physical activity of people with dementia and their relative caregivers. Also the effect on the cognitive state and cardiovascular risk will be assessed.; Design: Clinical, multicentric and randomized trial. A simple random sampling to select 134 patients diagnosed with dementia will be carried out. After contacting their relatives, his/her participation in the trial will be requested. A basal assessment will be made and the participants will be asigned to control or intervention group (1:1).; Variables: The main measure will be the assessment of physical activity (podometer and 7-PAR) in patients and caregivers. In patients with dementia: ADAS-cog, functional degree and cardiovascular risk. In caregivers: cardiovascular risk, general health and quality of life.; Intervention: For 3 months, participants will receive instructions to do physical activity with an adapted program. This program will be designed and applied by Primary Health Care professionals in patients with dementia and their caregivers. The control group will receive regular care.; Analysis: An intention-to-treat analysis will be carried out by comparing the observed differences between basal, 6 and 12 months measures. Change in the mean of daily steps assessed with the podometer and 7-PAR will be the main result.; Discussion: If the main hypothesis is confirmed, it could be useful to improve the cognitive state of patients with dementia, as well as the cardiovascular risk of all of them. The results can be good to improve technical features of the devices that register the physical activity in the patients with dementia, and it could facilitate its commercialization.; Trial Registration: Clinical Identifier: NCT02044887.;

Bibtex Citation

@article{Rodriguez_S_nchez_2014, doi = {10.1186/1471-2377-14-63}, url = {}, year = 2014, publisher = {Springer Nature}, volume = {14}, number = {1}, pages = {63}, author = {Emiliano Rodriguez-S{'{a}}nchez and Jos{'{e}} Criado-Guti{'{e}}rrez and Sara Mora-Sim{'{o}}n and M Muriel-Diaz and Manuel A G{'{o}}mez-Marcos and Jos{'{e}} I Recio-Rodr{'{i}}guez and M Patino-Alonso and Luis F Valero-Juan and Jos{'{e}} A Maderuelo-Fernandez and Luis Garc{'{i}}a-Ortiz}, title = {Physical activity program for patients with dementia and their relative caregivers: randomized clinical trial in Primary Health Care ({AFISDEMyF} study)}, journal = {{BMC} Neurology} }


activity, cardiovascular, caregivers, dementia, health, humans, intervention, physical, physical therapy modalities, rehabilitation, research design, risk

Countries of Study


Types of Dementia

Dementia (general / unspecified)

Types of Study

Randomised Controlled Trial

Type of Outcomes

ADLs/IADLs, Carers’ Mental Health, Carers’ Physical Health, Cognition, Prevention and/or management of co-morbidities, Quality of Life of Carer


Primary Care

Type of Interventions

Intervention for Carers, Non-pharmacological Treatment

Non-Pharmaceutical Interventions

Exercise (inc. dancing)

Carer Focussed Interventions

Wellbeing interventions (e.g. massage, physical health checks, relaxation techniques, self-care advice)