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This database contains 160 studies, archived under the term: "Background"

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Nutritional treatment of aged individuals with Alzheimer disease living at home with their spouses: study protocol for a randomized controlled trial

Background: Nutritional status often deteriorates in Alzheimer’s disease (AD). Less is known about whether nutritional care reverses malnutrition and its harmful consequences in AD. The aim of this study is to examine whether individualized nutritional care has an effect on weight, nutrition, health, physical functioning, and quality of life in older individuals with AD and […]

Staff outcomes from the caring for aged dementia care resident study (CADRES): a cluster randomised trial

Background: Dementia care mapping and person centred care are well-accepted as processes for improving care and well-being for persons with dementia living in the residential setting. However, the impact of dementia care mapping and person centred care on staff has not been well researched.; Objectives: The impact of person centred care and dementia care mapping […]

Relapse risk after discontinuation of risperidone in Alzheimer’s disease

Background: Among patients with Alzheimer’s disease who have had a response to antipsychotic medication for psychosis or agitation-aggression, the risk of a recurrence of symptoms after discontinuation of the medication has not been established.; Methods: Patients with Alzheimer’s disease and psychosis or agitation-aggression received open-label treatment with risperidone for 16 weeks. Those who had a […]

The costs and benefits of an integrated approach to dementia

Background: An integrated approach to dementia is generally recommended because no one discipline is adequately equipped it deal with the complex psychic, physical and social problems that are inherent in dementia. A multidisciplinary approach, however, leads inevitably to higher costs. It is not known what the cost/benefit ratio will be.; Aim: To describe our research […]

Effectivity of early psychosocial counselling for family caregivers in general practioner based dementia care

Background: Psychoeducation and professional support of family caregivers are regarded as important aspects in dementia care. In the context of a general practitioner’s (GP) based dementia care project we investigated if professional counselling after making a diagnosis of dementia can reduce the development of depression in family caregivers.; Methods: 42 patients with dementia and their […]

Effects of a psychological group intervention on neuropsychiatric symptoms and communication in Alzheimer’s dementia

Background: Outcomes of a multicomponent psychological intervention designed for the treatment of neuropsychiatric symptoms, communicative and emotional deficits in patients with mild to moderate Alzheimer’s dementia were evaluated in a controlled trial. Core components of the program were milieu therapy interventions and music therapy.; Patients and Methods: A total of 49 patients were involved into […]

Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people

Background: Curcumin extracts of turmeric are proposed to produce health benefits. To date, human intervention studies have focused mainly on people with existing health problems given high doses of poorly absorbed curcumin. The purpose of the current study was to check whether in healthy people, a low dose of a lipidated curcumin extract could alter […]

Role of a multidisciplinary program in improving outcomes in cognitively impaired heart failure older patients

Background: Cognitive impairment (CI) frequently complicates Heart failure (HF) and is associated with increased mortality and morbidity. Previous studies reported that nurse-lead home-based multidisciplinary program (MP) may not improve the prognosis of this high-risk group. In the present study, we analysed the relative effectiveness of an integrated hospital-based MP in patients with cognitive impairment.; Methods: […]

A benefit-finding intervention for family caregivers of persons with Alzheimer disease: study protocol of a randomized controlled trial

Background: Caregivers of relatives with Alzheimer’s disease are highly stressed and at risk for physical and psychiatric conditions. Interventions are usually focused on providing caregivers with knowledge of dementia, skills, and/or support, to help them cope with the stress. This model, though true to a certain extent, ignores how caregiver stress is construed in the […]

Transdermal is better than oral: observational research of the satisfaction of caregivers of patients with Alzheimer’s disease treated with rivastigmine

Background and Aims: Poor adherence to anti-dementia drugs is common among patients with Alzheimer’s disease. This study evaluated whether caregivers were more satisfied with, and patients more adherent to, transdermal rivastigmine than oral rivastigmine.; Methods: Neurologists, psychiatrists and geriatricians collected sociodemographic and clinical data from 1,078 patients and administered the Treatment Satisfaction with Medicines (SATMED-Q) […]

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