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This database contains 66 studies, archived under the term: "General population health promotion"

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Decreased self-reported cognitive failures after memory training

In recent years, attention has been focused on investigating the effectiveness of composite memory intervention programs with different age and diagnostics groups. The goal of this study was to measure changes in cognitive lapses by Cognitive Failure Questionnaire (CFQ) in a large trained, dementia free group (Mini-Mental State Examination [MMSE] > 26). The CFQ was […]

Treino de memória episódica com ênfase em categorização para idosos sem demência e depressão. = Episodic memory training with emphasis on categorization for older adults without dementia and depression

Aging may lead to cognitive changes, especially in memory. Yet, research suggests that older adults may improve memory performance after training. The present study aimed at evaluating the effects of episodic memory training offered to healthy Brazilian older adults. Fifty seven participants were randomly divided into control group (COG = 26) and experimental group (EXG […]

Vitamins B₁₂, B₆, and folic acid for cognition in older men

[Correction Notice: An erratum for this article was reported in Vol 77(8) of Neurology (see record [rid]2011-21984-022[/rid]). In the original article, the daily dose of vitamin B12 used in the trial was reported as 400 μg, but it should have been 500 μg.] Objective: To investigate whether supplementing older men with vitamins B12, B6, and […]

Addressing population aging and Alzheimer’s disease through the Australian Imaging Biomarkers and Lifestyle Study: Collaboration with the Alzheimer’s Disease Neuroimaging Initiative

The Australian Imaging Biomarkers and Lifestyle (AIBL) study is a longitudinal study of 1112 volunteers from healthy, mild cognitive impairment, and Alzheimer’s disease (AD) populations who can be assessed and followed up for prospective research into aging and AD. AIBL aims to improve understanding of the pathogenesis, early clinical manifestation, and diagnosis of AD, and […]

Interaction effects of education and health status on cognitive change: A 6-year follow-up of the Maastricht Aging Study

Objectives: The aim of this study was to test for interactions between education and health status (i.e., physical, social, and psychological functioning) with respect to baseline cognitive performance and change over 6 years. Method: Longitudinal data from the Maastricht Aging Study of 1344 men and women aged 24-47 and 49-77 were used. Results: Education by […]

Ginkgo biloba prevention trials: More than an ounce of prevention learned

Objective: To determine effectiveness of G biloba vs placebo in reducing the incidence of all-cause dementia and Alzheimer disease (AD) in elderly individuals with normal cognition and those with mild cognitive impairment (MCI). Design, Setting, and Participants: Randomized, double-blind, placebo-controlled clinical trial conducted in 5 academic medical centers in the United States between 2000 and […]

Cost-effectiveness of a health intervention program with risk reductions for getting demented: results of a Markov model in a Swedish/Finnish setting

Risk scores based on modifiable factors have recently been developed for dementia. This study aims to estimate the cost-effectiveness of a potential preventive intervention program meant to lower the score related to increased dementia risk. Analyses were based on a Markov model adapted to Swedish circumstances. Risk score categories and risk probabilities were derived from […]

Statins and serum cholesterol’s associations with incident dementia and mild cognitive impairment

Background: Statin use and serum cholesterol reduction have been proposed as preventions for dementia and mild cognitive impairment (MCI). Methods: 1604 and 1345 eligible participants from the Baltimore Longitudinal Study of Aging (BLSA) were followed after age 50 for a median time of around 25 years, to examine the incidence of dementia (n = 259) […]

Diuretic use is associated with better learning and memory in older adults in the Ginkgo Evaluation of Memory Study

Background: To investigate the association between diuretics, angiotensin-converting enzyme inhibitors (ACE-I), angiotensin II receptor blockers (AT2RB), and cognitive function.; Methods: This post hoc analysis of the randomized controlled Ginkgo Evaluation of Memory Study trial focuses on 3069 nondemented community-dwelling participants aged >75 years. At baseline visit, detailed information about medication use was collected and five […]

Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial

Cost-effective strategies to maintain healthy active lifestyle in aging populations are required to address the global burden of age-related diseases. ASPREE will examine whether the potential primary prevention benefits of low dose aspirin outweigh the risks in older healthy individuals. Our primary hypothesis is that daily oral 100 mg enteric-coated aspirin will extend a composite […]

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