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Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial
Porsteinsson, Anton P.,
Drye, Lea T.,
Pollock, Bruce G.,
Devanand, D. P.,
Frangakis, Constantine,
Ismail, Zahinoor,
Marano, Christopher,
Meinert, Curtis L.,
Mintzer, Jacobo E.,
Munro, Cynthia A.,
Pelton, Gregory,
Rabins, Peter V.,
Rosenberg, Paul B.,
Schneider, Lon S.,
Shade, David M.,
Weintraub, Daniel,
Yesavage, Jerome,
Lyketsos, Constantine G.
...evaluate the efficacy of citalopram for agitation in patients with Alzheimer disease. Key secondary objectives examined effects of citalopram on function, caregiver distress, safety, cognitive safety, and tolerability.; Design, Setting,...
Effects of a psychological intervention in a primary health care center for caregivers of dependent relatives: a randomized trial
Rodriguez-Sanchez, E.,
Patino-Alonso, M. C.,
Mora-Simon, S.,
Gomez-Marcos, M. A.,
Perez-Penaranda, A.,
Losada-Baltar, A.,
Garcia-Ortiz, L.
Purpose: To assess, in the context of Primary Health Care (PHC), the effect of a psychological intervention in mental health among caregivers (CGs) of dependent relatives.; Design and...
Effects of dementia-care mapping on residents and staff of care homes: a pragmatic cluster-randomised controlled trial
van de Ven, Geertje,
Draskovic, Irena,
Adang, Eddy M. M.,
Donders, Rogier,
Zuidema, Sytse U.,
Koopmans, Raymond T. C. M.,
Vernooij-Dassen, Myrra J. F. J.
...staff stress and job satisfaction. The nursing staff made all measurements at baseline and two follow-ups at 4-month intervals. We used linear mixed-effect models to test treatment and time effects.;...
Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial
Livingston, G.,
Barber, J.,
Rapaport, P.,
Knapp, M.,
Griffin, M.,
King, D.,
Livingston, D.,
Mummery, C.,
Walker, Z.,
Hoe, J.,
Sampson, E. L.,
Cooper, C.
...manual based coping intervention comprising eight sessions and delivered by supervised psychology graduates to carers of family members with dementia. The programme consisted of psychoeducation about dementia, carers’ stress, and...
A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: effects on mental health, cognition, and telomerase activity
Lavretsky, H.,
Epel, E.S.,
Siddarth, P.,
Nazarian, N.,
Cyr, N. St.,
Khalsa, D.S.,
Lin, J.,
Blackburn, E.,
Irwin, M.R.
...depressive symptoms. This improvement is accompanied by an increase in telomerase activity suggesting improvement in stress-induced cellular aging. These results need to be confirmed in a larger sample.; Copyright ©...
Effect of shunt operation on idiopathic normal pressure hydrocephalus patients in reducing caregiver burden: evidence from SINPHONI
Kazui, Hiroaki,
Mori, Etsuro,
Hashimoto, Masaaki,
Ishikawa, Masatsune,
Hirono, Nobutsugu,
Takeda, Masatoshi
...also reduce caregiver burden.; Methods: The personal strain (PS) and role strain (RS) factors, which are related to the stress and constraints, respectively, on the caregivers of 81 iNPH patients...
Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study
O'Callaghan, Nathan,
Parletta, Natalie,
Milte, Catherine M.,
Benassi-Evans, Bianca,
Fenech, Michael,
Howe, Peter R.C.
...Objectives: Excessive shortening of the telomeric ends of chromosomes is a marker of accelerated aging. Oxidative stress and nutritional deficiency may influence this process. The aim of this study...