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Effect of shunt operation on idiopathic normal pressure hydrocephalus patients in reducing caregiver burden: evidence from SINPHONI


Kazui, Hiroaki, Mori, Etsuro, Hashimoto, Masaaki, Ishikawa, Masatsune, Hirono, Nobutsugu, Takeda, Masatoshi


Dementia And Geriatric Cognitive Disorders, Volume: 31, No.: 5, Pages.: 363-370

Year of Publication



Background/aims: Patients with idiopathic normal pressure hydrocephalus (iNPH) are often given shunt operations to reduce the triad symptoms (cognitive impairment, gait disturbance and urinary disturbance). We examined whether they also reduce caregiver burden.; Methods: The personal strain (PS) and role strain (RS) factors, which are related to the stress and constraints, respectively, on the caregivers of 81 iNPH patients were evaluated with the Zarit burden interview (ZBI) and each of the triad symptoms was evaluated with the iNPH grading scale (iNPHGS) before and 1 year after the shunt operation.; Results: Each of the iNPHGS scores, the total ZBI score and PS factor significantly improved after the shunt operation, but the RS factor did not. The improvement of cognitive impairment was the major factor in reducing caregiver burden.; Conclusion: Shunt operations reduced the caregiver burden of iNPH patients.; Copyright © 2011 S. Karger AG, Basel.

Bibtex Citation

@article{Kazui_2011, doi = {10.1159/000328625}, url = {}, year = 2011, publisher = {S. Karger {AG}}, volume = {31}, number = {5}, pages = {363--370}, author = {Hiroaki Kazui and Etsuro Mori and Masaaki Hashimoto and Masatsune Ishikawa and Nobutsugu Hirono and Masatoshi Takeda}, title = {Effect of Shunt Operation on Idiopathic Normal Pressure Hydrocephalus Patients in Reducing Caregiver Burden: Evidence from {SINPHONI}}, journal = {Dementia and Geriatric Cognitive Disorders} }


activities of daily living, age factors, aged, aged, 80 and over, and, caregivers, carers, cerebral ventricles, cognitive, cohort studies, cost of illness, female, humans, hydrocephalus, hydrocephalus, normal pressure, idiopathic, impact, impairment, in, inph, intervention, interview psychological, japan, magnetic resonance imaging, male, middle aged, neuropsychological tests, normal, on, pathology, patients, pressure, psychology, reduce, sex factors, surgery, surgical, to, treatment outcome, ventriculoperitoneal shunt

Countries of Study


Types of Dementia

Mild Cognitive Impairment (MCI)

Types of Study

Before and After Study

Type of Outcomes

Carer Burden (instruments measuring burden)

Type of Interventions

Intervention for Carers

Carer Focussed Interventions