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This database contains 1433 studies, archived under the term: ""

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A community-based approach to trials of aerobic exercise in aging and Alzheimer’s disease

The benefits of exercise for aging have received considerable attention in both the popular and academic press. The putative benefits of exercise for maximizing cognitive function and supporting brain health have great potential for combating Alzheimer’s disease (AD). Aerobic exercise offers a low-cost, low-risk intervention that is widely available and may have disease modifying effects. […]

From Alzheimer’s disease retrogenesis: a new care strategy for patients with advanced dementia

There is evidence that exercise may reduce the progressive cognitive dysfunction of Alzheimer’s disease (AD). However, no previous investigation has studiethe acute effects of adapted games (AG) on patients with AD. The aim of this study was to examine the acute effects of AG on the agitated behavior (rating scale Agitated Behavior Rating Scale [ABRS]) […]

Study protocol: a randomised controlled trial of the effects of a multi-modal exercise program on cognition and physical functioning in older women

Background: Intervention studies testing the efficacy of cardiorespiratory exercise have shown some promise in terms of improving cognitive function in later life. Recent developments suggest that a multi-modal exercise intervention that includes motor as well as physical training and requires sustained attention and concentration, may better elicit the actual potency of exercise to enhance cognitive […]

Effects of two different intensities of aerobic exercise on elderly people with mild cognitive impairment: a randomized pilot study

Objective: To evaluate the effect of different intensities of aerobic exercise on elderly people with mild cognitive impairment.; Design: A randomized trial.; Setting: Residential care homes for elderly people.; Subjects: Forty-eight patients were included in the study.; Interventions: The patients were randomized in three groups. Group A performed aerobic exercise at 40% of heart rate […]

Effectiveness of Physio Acoustic Sound (PAS) therapy in demented nursing home residents with nocturnal restlessness: study protocol for a randomized controlled trial

Background: Many older people with neuropsychiatric disorders such as Alzheimer’s disease and frontotemporal dementia suffer from sleeping problems and often show nocturnal restlessness. Professionals and informal carers face considerable problems in solving these problems. Attempts to diminish these problems with medication in a safe and responsible manner have proven hardly effective or not effective at […]

Dementelcoach: effect of telephone coaching on carers of community-dwelling people with dementia

Background: Dementelcoach is a new telephone intervention to support informal caregivers of community dwelling people with dementia. The effectiveness of this intervention was evaluated on burden and mental health problems of informal caregivers.; Methods: A pre-test/post-test comparison group design was used with three groups of informal caregivers.Two of the groups were experimental and received either […]

Does theatre improve the quality of life of people with dementia?

Background: A new communication method, the “Veder method”, has recently been developed. Caregivers are trained to apply this method in a group activity (“living-room theatre activity”) for people with dementia in which theatrical stimuli are used in combination with proven emotion-oriented care methods. The aim of this exploratory study was to evaluate the added value […]

The study protocol of a cluster-randomised controlled trial of family-mediated personalised activities for nursing home residents with dementia

Background: Following admission to a nursing home, the feelings of depression and burden that family carers may experience do not necessarily diminish. Additionally, they may experience feelings of guilt and grief for the loss of a previously close relationship. At the same time, individuals with dementia may develop symptoms of depression and agitation (BPSD) that […]

Improving person-centred care in nursing homes through dementia-care mapping: design of a cluster-randomised controlled trial

Background: The effectiveness and efficiency of nursing-home dementia care are suboptimal: there are high rates of neuropsychiatric symptoms among the residents and work-related stress among the staff. Dementia-care mapping is a person-centred care method that may alleviate both the resident and the staff problems. The main objective of this study is to evaluate the effectiveness […]

Study of the effects of vinpocetin on cognitive functions

Introduction: Chronic cerebral hypoperfusion is a risk factor for the development of certain types of dementia. Mild cognitive impairment is a stage of predementia condition, because the symptoms are similar but not as severe as the symptoms in patients with dementia. Vinpocetine, due to its complex mechanism of action, has an important role in the […]

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