This database contains 343 studies, archived under the term: "therapy"
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The cost-effectiveness of a family meetings intervention to prevent depression and anxiety in family caregivers of patients with dementia: a randomized trial
Joling, Karlijn J,
Bosmans, Judith E,
van Marwijk, Harm WJ,
van der Horst, Henriëtte E,
Scheltens, Philip,
Vroomen, Janet L,
van Hout, Hein PJ
Background: Dementia imposes a heavy burden on health and social care systems as well as on family caregivers who provide a substantial portion of the care. Interventions that effectively support caregivers may prevent or delay patient institutionalization and hence be cost-effective. However, evidence about the cost-effectiveness of such interventions is scarce. The aim of this […]
Treatment outcomes of a crisis intervention program for dementia with severe psychiatric complications: the Kansas bridge project
Johnson, D. K.,
Niedens, M.,
Wilson, J. R.,
Swartzendruber, L.,
Yeager, A.,
Jones, K.
Purpose: Although declines in memory and attention are hallmark symptoms of Alzheimer’s disease (AD), noncognitive symptoms are prevalent. Over 80% of individuals will experience neuropsychiatric symptoms, which complicates symptom profiles. Research indicates a community-integrated response to dementia crisis can reduce negative consequences attributed to crisis including increased caregiver burden, increased health care costs, and premature […]
Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy use
Jacobs, Emily G.,
Kroenke, Candyce,
Lin, Jue,
Epel, Elissa S.,
Kenna, Heather A.,
Blackburn, Elizabeth H.,
Rasgon, Natalie L.
Apolipoprotein-ε4 (APOE-ε4) is a major genetic risk factor for cognitive decline, Alzheimer’s disease (AD) and early mortality. An accelerated rate of biological aging could contribute to this increased risk. Here, we determined whether APOE-ε4 status impacts leukocyte telomere length (TL) and the rate of cellular senescence in healthy mid-life women and, further, whether hormone replacement […]
Keeping up health promotion practices in specialized day care units for people with dementia
Background: Health promotion practices hold promises for elderly individuals’ quality of life. This article shows that such practices can be promoted in specialized day care units for individuals with dementia.; Method: Group interviews with 8 groups of staff (comprising 24 staff members) in 3 day care units.; Results: Rather than referring directly to health promotion […]
Potential impact of amyloid imaging on diagnosis and intended management in patients with progressive cognitive decline
Grundman, Michael,
Pontecorvo, Michael J.,
Salloway, Stephen P.,
Doraiswamy, P. Murali,
Fleisher, Adam S.,
Sadowsky, Carl H.,
Nair, Anil K.,
Siderowf, Andrew,
Lu, Ming,
Arora, Anupa K.,
Agbulos, Abigail,
Flitter, Matthew L.,
Krautkramer, Michael J.,
Sarsour, Khaled,
Skovronsky, Daniel M.,
Mintun, Mark A.
Florbetapir F18 has been approved by the Food and Drug Administration for in vivo assessment of amyloid pathology in patients undergoing evaluation for Alzheimer disease (AD). The aim of this study was to determine the impact of amyloid imaging on the diagnoses and management of patients undergoing evaluation for cognitive decline. Patients were recruited to […]
Telephone-based, cognitive-behavioral therapy for African American dementia caregivers with depression: initial findings
Glueckauf, Robert L.,
Davis, W. Shuford,
Willis, Floyd,
Sharma, Dinesh,
Gustafson, David J.,
Hayes, Jocelyn,
Stutzman, Mary,
Proctor, James,
Kazmer, Michelle M.,
Murray, Leticia,
Shipman, Judith,
McIntyre, Vera,
Wesley, Lonnie,
Schettini, Gabriel,
Xu, Jian,
Parfitt, Francine,
Graff-Radford, Neill,
Baxter, Cynthia,
Burnett, Kathleen,
Noël, La Tonya,
Haire, Kambria,
Springer, Jane
Objectives: Discuss initial findings of a randomized clinical trial comparing the effects of telephone-based and face-to-face (f-to-f) cognitive-behavioral therapy (CBT) on changes in caregiver (CG) burden, assistance support, depression, and health status for African American (AA) CGs with depression.; Design: Pilot study using a prepost, two-group design with 14 enrolled and randomized participants.; Measures: Subjective […]