This database contains 15 studies, archived under the term: "geriatrics"
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Memantine in moderately-severe-to-severe Alzheimer’s disease: A postmarketing surveillance study
Clerici, Francesca,
Vanacore, Nicola,
Elia, Antonietta,
Spila-Alegiani, Stefania,
Pomati, Simone,
Da Cas, Roberto,
Raschetti, Roberto,
Mariani, Claudio
Background: Postmarketing surveillance studies (PMS) are an important tool for evaluating a drug’s effectiveness and safety in clinical practice. To our knowledge, no PMS on memantine monotherapy for moderately-severe-to-severe Alzheimer’s disease (AD) according to National Institute of Neurological and Communicative Disorders and Stroke—Alzheimer’s Disease and Related Disorders Association criteria has been conducted to date. Objective: […]
Psychosocial group intervention to enhance self-management skills of people with dementia and their caregivers: study protocol for a randomized controlled trial
Laakkonen, Marja-Liisa,
Hölttä, Eeva H.,
Savikko, Niina,
Strandberg, Timo E.,
Suominen, Merja,
Pitkälä, Kaisu H.
Background: After diagnosis of a dementing illness, patients and their spouses have many concerns related to the disease and their future. This often leads to poor psychological well-being and reduced health-related quality of life (HRQoL) of the family. Support for self-management skills has been proven to be an effective method to improve prognosis of asthma, […]
A practice-based intervention to improve primary care for falls, urinary incontinence, and dementia
Wenger, Neil S.,
Roth, Carol P.,
Shekelle, Paul G.,
Young, Roy T.,
Solomon, David H.,
Kamberg, Caren J.,
Chang, John T.,
Louie, Rachel,
Higashi, Takahiro,
MacLean, Catherine H.,
Adams, John,
Min, Lillian C.,
Ransohoff, Kurt,
Hoffing, Marc,
Reuben, David B.
Objectives: To determine whether a practice-based intervention can improve care for falls, urinary incontinence, and cognitive impairment.; Design: Controlled trial.; Setting: Two community medical groups.; Participants: Community-dwelling patients (357 at intervention sites and 287 at control sites) aged 75 and older identified as having difficulty with falls, incontinence, or cognitive impairment.; Intervention: Intervention and control […]
Vitamins B(12), B(6), and folic acid for cognition in older men
Ford, A. H.,
Flicker, L.,
Alfonso, H.,
Thomas, J.,
Clarnette, R.,
Martins, R.,
Almeida, O. P.
Objective: To investigate whether supplementing older men with vitamins B(12), B(6), and folic acid improves cognitive function.; Methods: The investigators recruited 299 community-representative hypertensive men 75 years and older to a randomized, double-blind controlled clinical trial of folic acid, vitamin B(6), and B(12) supplementation vs placebo over 2 years. The primary outcome of interest was […]
The Indiana Alzheimer Disease Center’s Symposium on Mild Cognitive Impairment. Cognitive training in older adults: Lessons from the ACTIVE study
Unverzagt, Frederick,
Smith, David,
Rebok, George,
Marsiske, Michael,
Morris, John,
Jones, Richard,
Willis, Sherry,
Ball, Karlene,
King, Jonathan,
Koepke, Kathy,
Stoddard, Anne,
Tennstedt, Sharon
This paper is based on a presentation made during the Indiana Alzheimer Disease Center’s Symposium on Mild Cognitive Impairment on April 19, 2008. The results of the ACTIVE study (Advanced Cognitive Training for Independent and Vital Elderly) were presented at the symposium including review of previously published study findings. The ACTIVE study is a multicenter, […]
The Montreal Cognitive Assessment (MoCA) in geriatric rehabilitation: psychometric properties and association with rehabilitation outcomes
Sweet, Lisa,
Van Adel, Mike,
Metcalf, Valerie,
Wright, Lisa,
Harley, Anne,
Leiva, René,
Taler, Vanessa
Background: Cognitive status has been reported to be an important predictor of rehabilitation outcome. The Montreal Cognitive Assessment (MoCA) was designed to overcome some of the limitations of established cognitive screening tools such as the Mini-Mental State Examination (MMSE). The purpose of this study is to evaluate the psychometric characteristics of the MoCA as a […]
Cost analysis of early psychosocial intervention in Alzheimer’s disease
Søgaard, Rikke,
Sørensen, Jan,
Waldorff, Frans B.,
Eckermann, Ane,
Buss, Dorthe V.,
Waldemar, Gunhild
Background/aim: To investigate the impact of early psychosocial intervention aimed at patients with Alzheimer’s disease (AD) and their caregivers on resource use and costs from a societal perspective.; Methods: Dyads of patients and their primary caregiver were randomised to intervention (n = 163) or control (n = 167) and followed for 3 years. Health care […]