This database contains 49 studies, archived under the term: "exercise therapy"
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Effects of multicomponent exercise on cognitive function in older adults with amnestic mild cognitive impairment: a randomized controlled trial
Suzuki, Takao,
Shimada, Hiroyuki,
Makizako, Hyuma,
Doi, Takehiko,
Yoshida, Daisuke,
Tsutsumimoto, Kota,
Anan, Yuya,
Uemura, Kazuki,
Lee, Sangyoon,
Park, Hyuntae
Background: To examine the effects of a multicomponent exercise program on the cognitive function of older adults with amnestic mild cognitive impairment (aMCI).; Design: Twelve months, randomized controlled trial;; Setting: Community center in Japan;; Participants: Fifty older adults (27 men) with aMCI ranging in age from 65 to 93 years (mean age, 75 years);; Intervention: […]
Does a multicomponent exercise program improve dual-task performance in amnestic mild cognitive impairment? A randomized controlled trial
Makizako, Hyuma,
Doi, Takehiko,
Shimada, Hiroyuki,
Yoshida, Daisuke,
Tsutsumimoto, Kota,
Uemura, Kazuki,
Suzuki, Takao
Background and Aims: There has been much interest in exercise interventions as a primary behavioral prevention strategy against cognitive decline. The aim of this study was to evaluate the effect of a multicomponent exercise program on physical and dual-task performances in community-dwelling older adults with amnestic mild cognitive impairment (aMCI).; Methods: Fifty older adults (23 […]
Physical training improves motor performance in people with dementia: a randomized controlled trial
Hauer, Klaus,
Schwenk, Michael,
Zieschang, Tania,
Essig, Marco,
Becker, Clemens,
Oster, Peter
Objectives: To determine whether a specific, standardized training regimen can improve muscle strength and physical functioning in people with dementia.; Design: Double-blinded, randomized, controlled trial with 3-month intervention and 3-month follow-up period in 2006 to 2009.; Setting: Outpatient geriatric rehabilitation.; Participants: Individuals with confirmed mild to moderate dementia, no severe somatic or psychological disease, and […]
Study protocol: EXERcise and cognition in sedentary adults with early-ONset dementia (EXERCISE-ON)
Hooghiemstra, Astrid M.,
Eggermont, Laura H.P.,
Scheltens, Philip,
van der Flier, Wiesje M.,
Bakker, Jet,
de Greef, Mathieu H. G.,
Koppe, Peter A.,
Scherder, Erik J.A.
Background: Although the development of early-onset dementia is a radical and invalidating experience for both patient and family there are hardly any non-pharmacological studies that focus on this group of patients. One type of a non-pharmacological intervention that appears to have a beneficial effect on cognition in older persons without dementia and older persons at […]
A randomized feasibility study of a 12-week community-based exercise program for people with Huntington’s disease
Busse, Monica,
Quinn, Lori,
Debono, Katy,
Jones, Karen,
Collett, Johnathan,
Playle, Rebecca,
Kelly, Mark,
Simpson, Sharon,
Backx, Karianne,
Wasley, David,
Dawes, Helen,
Rosser, Anne
BACKGROUND AND PURPOSE: The beneficial role of exercise as a treatment approach in Huntington’s disease (HD) has support from both preclinical work and small-scale studies; however, there have been no controlled studies of gym-based exercise in people with HD. This phase 2 randomized trial (ISRCTN 59910670) assessed feasibility, safety, acceptability, and benefit of a structured […]
Preventing loss of independence through exercise (PLIE): a pilot clinical trial in older adults with dementia
Barnes, D. E.,
Mehling, W.,
Wu, E.,
Beristianos, M.,
Yaffe, K.,
Skultety, K.,
Chesney, M. A.
BACKGROUND: Current dementia medications have small effect sizes, many adverse effects and do not change the disease course. Therefore, it is critically important to study alternative treatment strategies. The goal of this study was to pilot-test a novel, integrative group exercise program for individuals with mild-to-moderate dementia called Preventing Loss of Independence through Exercise (PLIE), […]
Preventing Loss of Independence through Exercise (PLIE): qualitative analysis of a clinical trial in older adults with dementia
Wu, E.,
Barnes, D. E.,
Ackerman, S. L.,
Lee, J.,
Chesney, M.,
Mehling, W. E.
OBJECTIVES: Preventing Loss of Independence through Exercise (PLIE) is a novel, integrative exercise program for individuals with dementia that combines elements of different conventional and complementary exercise modalities (e.g. tai-chi, yoga, Feldenkrais, and dance movement therapy) and focuses on training procedural memory for basic functional movements (e.g., sit-to-stand) while increasing mindful body awareness and facilitating […]
Commentary on “A roadmap for the prevention of dementia II. Leon Thal Symposium 2008.” The Multidomain Alzheimer Preventive Trial (MAPT): a new approach to the prevention of Alzheimer’s disease
Gillette-Guyonnet, Sophie,
Andrieu, Sandrine,
Dantoine, Thierry,
Dartigues, Jean-François,
Touchon, Jacques,
Vellas, B.
Background: Because no effective curative approaches are available, preventive approaches in the field of Alzheimer’s disease (AD) are needed. We present the design of the ongoing Multidomain Alzheimer Preventive Trial (MAPT) Study. Several previous studies suggested that many factors may be involved in the occurrence of AD at late ages. Because of the probable multifactorial […]