This database contains 1058 studies, archived under the term: "aged"
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The FABS trial: a randomised control trial of the effects of a 6-month physical activity intervention on adherence and long-term physical activity and self-efficacy in older adults with memory complaints
Cox, Kay L.,
Flicker, Leon,
Almeida, Osvaldo P.,
Xiao, Jianguo,
Greenop, Kathryn R.,
Hendriks, Jacqueline,
Phillips, Michael,
Lautenschlager, Nicola T.
Objective: The aim of this study is to assess in older adults with memory complaints, the effects of a 6-month home-based physical activity (PA) intervention on short-term adherence, short and long-term self-efficacy and the predictors of adherence.; Methods: Participants with memory complaints with or without mild cognitive impairment (MCI) were recruited from Perth, Western Australia […]
The impact of group music therapy on depression and cognition in elderly persons with dementia: a randomized controlled study
Chu, H.,
Yang, C.-Y.,
Lin, Y.,
Ou, K.-L.,
Lee, T.-Y.,
O'Brien, A. P.,
Chou, K.-R.
Objective: The aims of this study were to determine the effectiveness of group music therapy for improving depression and delaying the deterioration of cognitive functions in elderly persons with dementia.; Method: The study had a prospective, parallel-group design with permuted-block randomization. Older persons with dementia (N = 104) were randomly assigned to the experimental or […]
Tolerability and efficacy of memantine add-on therapy to rivastigmine transdermal patches in mild to moderate Alzheimer’s disease: a multicenter, randomized, open-label, parallel-group study
Choi, Seong Hye,
Park, Kyung Won,
Na, Duk L.,
Han, Hyun Jeong,
Kim, Eun-Joo,
Shim, Yong S.,
Lee, Jae-Hong,
The EXPECT Study Group,
Objective: To compare the tolerability and efficacy of combination therapy of memantine plus rivastigmine patch with rivastigmine patch monotherapy in patients with mild to moderate Alzheimer’s disease (AD).; Research Design and Methods: In this multicenter, randomized, open-label study, patients entered an 8-week run-in period (a 5 cm 2 rivastigmine patch for 4 weeks, then a […]
Mental and physical activities delay cognitive decline in older persons with dementia
Cheng, Sheung-Tak,
Chow, Pizza K.,
Song, You-Qiang,
Yu, Edwin C.S.,
Chan, Alfred C.M.,
Lee, Tatia M.C.,
Lam, John H.M.
Objectives: To examine the effects of cognitive stimulation (mahjong) and physical exercise (tai chi [TC]) on cognitive performance in persons with dementia.; Design: Cluster-randomized open-label controlled design.; Setting: Nursing homes.; Participants: One hundred ten residents, most of whom were cholinesterase-inhibitor naive. Inclusion criteria were Mini-Mental State Examination (MMSE) = 10-24 and suffering from at least very mild […]
Women have farther to fall: gender differences between normal elderly and Alzheimer’s disease in verbal memory engender better detection of Alzheimer’s disease in women
Chapman, Robert M.,
Mapstone, Mark,
Gardner, Margaret N.,
Sandoval, Tiffany C.,
McCrary, John W.,
Guillily, Maria D.,
Reilly, Lindsey A.,
DeGrush, Elizabeth
We analyzed verbal episodic memory learning and recall using the Logical Memory (LM) subtest of the Wechsler Memory Scale-III to determine how gender differences in AD compare to those seen in normal elderly and whether or not these differences impact assessment of AD. We administered the LM to both an AD and a Control group, […]
Continuous use of antipsychotics and its association with mortality and hospitalization in institutionalized Chinese older adults: an 18-month prospective cohort study
Chan, Tuen-Ching,
Luk, James Ka-Hay,
Shea, Yat-Fung,
Lau, Ka-Hin,
Chan, Felix Hon-Wai,
Yu, Gabriel Ka-Kui,
Chu, Leung-Wing
Background: Previous meta-analyses have suggested that antipsychotics are associated with increased mortality in dementia patients with behavioral and psychological symptoms (BPSD). Subsequent observational studies, however, have produced conflicting results. In view of this controversy and the lack of any suitable pharmacological alternative for BPSD, this study aimed to investigate the relationship between continuous use of […]