Glasser, Stephen P., Wadley, Virginia, Judd, Suzanne, Kana, Bhumika, Prince, Valerie, Jenny, Nancy, Kissela, Brett, Safford, Monika, Prineas, Ronald, Howard, George

Background: Statin use and type have been variably associated with impaired or improved cognitive performance.; Hypothesis: To assess the association of statin use and type (lipophilic vs hydrophilic) and cognitive impairment.; Methods: Cross-sectional analysis of 24 595 participants (7191 statin users and 17 404 nonusers) age > or = 45 years, from a population-based national […]

Snitz, Beth E., Unverzagt, Frederick W., Chang, Chung-Chou H., Bilt, Joni Vander, Gao, Sujuan, Saxton, Judith, Hall, Kathleen S., Ganguli, Mary

Background: Neuropsychological tests, including tests of language ability, are frequently used to differentiate normal from pathological cognitive aging. However, language can be particularly difficult to assess in a standardized manner in cross-cultural studies and in patients from different educational and cultural backgrounds. This study examined the effects of age, gender, education and race on performance […]

Liu, Hai, Gao, Sujuan, Hall, Kathleen S., Unverzagt, Frederick W., Lane, Kathleen A., Callahan, Christopher M., Hendrie, Hugh C.

Objectives: To report the results from a prospective cohort study on the association between blood pressure (BP) and cognitive function in elderly African Americans.; Design: Prospective cohort study conducted from 1997 to 2009.; Setting: Community-based study in Indianapolis.; Participants: African Americans aged 65 years or older (N = 3,145).; Measurements: At each assessment, participant cognitive […]

Glueckauf, Robert L., Davis, W. Shuford, Willis, Floyd, Sharma, Dinesh, Gustafson, David J., Hayes, Jocelyn, Stutzman, Mary, Proctor, James, Kazmer, Michelle M., Murray, Leticia, Shipman, Judith, McIntyre, Vera, Wesley, Lonnie, Schettini, Gabriel, Xu, Jian, Parfitt, Francine, Graff-Radford, Neill, Baxter, Cynthia, Burnett, Kathleen, Noël, La Tonya, Haire, Kambria, Springer, Jane

Objectives: Discuss initial findings of a randomized clinical trial comparing the effects of telephone-based and face-to-face (f-to-f) cognitive-behavioral therapy (CBT) on changes in caregiver (CG) burden, assistance support, depression, and health status for African American (AA) CGs with depression.; Design: Pilot study using a prepost, two-group design with 14 enrolled and randomized participants.; Measures: Subjective […]

Czaja, Sara J., Loewenstein, David, Schulz, Richard, Nair, Sankaran N., Perdomo, Dolores

Background/objectives: Available services and intervention programs for dementia caregivers are often underutilized because of issues such as cost, logistics, lack of knowledge about available services, or insufficient support from others. Information technologies offer the potential of removing these barriers and facilitating the ability of caregivers to access needed support. This project evaluated the feasibility and […]

Carlson, M. C., Erickson, K. I., Kramer, A. F., Voss, M. W., Bolea, N., Mielke, M., McGill, S., Rebok, G. W., Seeman, T., Fried, L. P.

Objective: To determine whether Experience Corps (EC), a social service program, would improve age-vulnerable executive functions and increase activity in brain regions in a high-risk group through increased cognitive and physical activity.; Methods: Eight community-dwelling, older female volunteers and nine matched wait-list controls were recruited to serve in the ongoing EC: Baltimore program in three […]