This database contains 154 studies, archived under the term: "UK"
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Maintenance Cognitive Stimulation Therapy (CST) for dementia: a single-blind, multi-centre, randomized controlled trial of Maintenance CST vs. CST for dementia
Aguirre, Elisa,
Spector, Aimee,
Hoe, Juanita,
Russell, Ian T.,
Knapp, Martin,
Woods, Robert T,
Orrell, Martin
Background: Psychological treatments for dementia are widely used in the UK and internationally, but only rarely have they been standardised, adequately evaluated or systematically implemented. There is increasing recognition that psychosocial interventions may have similar levels of effectiveness to medication, and both can be used in combination. Cognitive Stimulation Therapy (CST) is a 7-week cognitive-based […]
Self-management in early-stage dementia: a pilot randomised controlled trial of the efficacy and cost-effectiveness of a self-management group intervention (the SMART study)
Quinn, Catherine,
Anderson, Daniel,
Toms, Gill,
Whitaker, Rhiannon,
Edwards, Rhiannon Tudor,
Jones, Carys,
Clare, Linda
Background: The possibility of living well with a long-term condition has been identified as centrally relevant to the needs of people living with dementia. Growing numbers of people with early-stage dementia are contributing accounts that emphasise the benefits of actively engaging in managing the condition. Self-management interventions share the common objectives of educating about the […]
Does telecare prolong community living in dementia? A study protocol for a pragmatic, randomised controlled trial
Leroi, Iracema,
Woolham, John,
Gathercole, Rebecca,
Howard, Robert,
Dunk, Barbara,
Fox, Chris,
O'Brien, John,
Bateman, Andrew,
Poland, Fiona,
Bentham, Peter,
Burns, Alistair,
Davies, Anna,
Forsyth, Kirsty,
Gray, Richard,
Knapp, Martin,
Newman, Stanton,
McShane, Rupert,
Ritchie, Craig
Background: Assistive technology and telecare (ATT) are relatively new ways of delivering care and support to people with social care needs. It is claimed that ATT reduces the need for community care, prevents unnecessary hospital admission, and delays or prevents admission into residential or nursing care. The current economic situation in England has renewed interest […]
Maintenance Cognitive Stimulation Therapy (CST) in practice: study protocol for a randomized controlled trial
Streater, Amy,
Spector, Aimee,
Aguirre, Elisa,
Hoe, Juanita,
Hoare, Zoe,
Woods, Robert,
Russell, Ian,
Orrell, Martin
Background: Cognitive Stimulation Therapy (CST) is a psychosocial evidence-based group intervention for people with dementia recommended by the UK NICE guidelines. In clinical trials, CST has been shown to improve cognition and quality of life, but little is known about the best way of ensuring implementation of CST in practice settings. A recent pilot study […]
English longitudinal study of aging: Can Internet/E-mail use reduce cognitive decline?
Xavier, A. J.,
d'Orsi, E.,
de Oliveira, C. M.,
Orrell, M.,
Demakakos, P.,
Biddulph, J. P.,
Marmot, M. G.
Background: Cognitive decline is a major risk factor for disability, dementia, and death. The use of Internet/E-mail, also known as digital literacy, might decrease dementia incidence among the older population. The aim was to investigate whether digital literacy might be associated with decreased cognitive decline in older adulthood. Methods: Data from the English Longitudinal Study […]
The long-term efficacy and tolerability of donepezil in patients with vascular dementia
Wilkinson, David,
Róman, Gustavo,
Salloway, Stephen,
Hecker, Jane,
Boundy, Karyn,
Kumar, Dinesh,
Posner, Holly,
Schindler, Rachel
Objective: To determine the long-term tolerability and efficacy of donepezil in patients with vascular dementia (VaD).; Methods: International, multicentre, open-label, 30-week extension study of two 24-week, randomised, double-blind, placebo-controlled studies. Participants were ambulatory adults (59% female; mean age, 74.7 +/- 0.3) with a diagnosis of possible or probable VaD and without a diagnosis of Alzheimer’s […]
Tailored educational intervention for primary care to improve the management of dementia: the EVIDEM-ED cluster randomized controlled trial
Wilcock, Jane,
Iliffe, Steve,
Griffin, Mark,
Jain, Priya,
Thuné-Boyle, Ingela,
Lefford, Frances,
Rapp, David
Background: Early diagnosis of dementia is important because this allows those with dementia and their families to engage support and plan ahead. However, dementia remains underdetected and suboptimally managed in general practice. Our objective was to test the effect of a workplace-based tailored educational intervention developed for general practice on the clinical management of people […]
Providing activity for people with dementia in care homes: a cluster randomised controlled trial
Wenborn, Jennifer,
Challis, David,
Head, Jenny,
Miranda-Castillo, Claudia,
Popham, Carolyn,
Thakur, Ruchi,
Illes, Jacqueline,
Orrell, Martin
Background: Activity levels remain low in care homes, but activity engagement can enhance residents’ quality of life.; Aim: This study aimed to assess an occupational therapy programme designed to enable care home staff to increase activity provision.; Method: A cluster randomised controlled trial with blinded assessment of outcome was conducted. A total of 210 residents […]