This database contains 15 studies, archived under the term: "major depression"
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The effects of a support group on dementia caregivers’ burden and depression
Chu, Hsin,
Yang, Chyn-Yng,
Liao, Yen-Hsueh,
Chang, Lu- I.,
Chen, Chiung-Hua,
Lin, Chun-Chieh,
Chou, Kuei-Ru
Objective: The aim of the study is to investigate the effects of a support group on depression levels and burden among dementia caregivers in Taiwan. Method: An experimental, pre-intervention post-intervention control group design was used in this study. The experimental group received intervention consisting of a 12-week support group for dementia caregivers. A total of […]
Rivastigmine patch ameliorates depression in mild AD: Preliminary evidence from a 6-month open-label observational study
Spalletta, Gianfranco,
Gianni, Walter,
Giubilei, Franco,
Casini, Anna R.,
Sancesario, Giuseppe,
Caltagirone, Carlo,
Cravello, Luca
Here we investigated the effect of the rivastigmine patch alone on depression in 50 mild Alzheimer’s Disease (AD) patients with comorbid major depressive episode (MDE). First diagnosis acetyl-cholinesterase inhibitor and psychoactive drug-free outpatients (n = 50) were recruited in memory clinics and reassessed after 3 and 6 months. Global cognitive functioning, depressive symptoms and MDE […]
Physical activity and cognitive functioning in the oldest old: Within- and between-person cognitive activity and psychosocial mediators
Robitaille, Annie,
Muniz, Graciela,
Lindwall, Magnus,
Piccinin, Andrea M.,
Hoffman, Lesa,
Johansson, Boo,
Hofer, Scott M.
The current study examines the role of social contact intensity, cognitive activity, and depressive symptoms as within- and between-person mediators for the relationships between physical activity and cognitive functioning. All three types of mediators were considered simultaneously using multilevel structural equations modeling with longitudinal data. The sample consisted of 470 adults ranging from 79.37 to […]
Foot massage versus quiet presence on agitation and mood in people with dementia: A randomised controlled trial
Moyle, Wendy,
Cooke, Marie Louise,
Beattie, Elizabeth,
Shum, David H.K.,
O’Dwyer, Siobhan T.,
Barrett, Sue
Background: There is increasing interest in using complementary and alternative treatments to manage behavioural and psychological symptoms of dementia such as agitation, aggression and depressed mood. Objective: To compare the effect of foot massage (intervention) and quiet presence (control) on agitation and mood in people with dementia. Design: A randomised controlled trial using a within-subjects, […]
Cognitive training enhances pre-attentive neurophysiological responses in older adults ‘at risk’ of dementia
Mowszowski, Loren,
Hermens, Daniel F.,
Diamond, Keri,
Norrie, Louisa,
Cockayne, Nicole,
Ward, Philip B.,
Hickie, Ian B.,
Lewis, Simon J. G.,
Batchelor, Jennifer,
Naismith, Sharon L.
Background: With predicted increases in dementia incidence, interventions targeting neuroplasticity and neuroprotection are required. Cognitive Training (CT) is an intervention which has been shown to improve aspects of cognition, but the pathophysiological mechanisms contributing to its efficacy are unknown. Objective:We aimed to explore the neurobiological correlates of CT using Mismatch Negativity (MMN), a neurophysiological marker […]
The effect of person-centred dementia care to prevent agitation and other neuropsychiatric symptoms and enhance quality of life in nursing home patients: A 10-month randomized controlled trial
Rokstad, Anne Marie Mork,
Røsvik, Janne,
Kirkevold, Øyvind,
Selbaek, Geir,
Saltyte Benth, Jurate,
Engedal, Knut
Aims: We examined whether Dementia Care Mapping (DCM) or the VIPS practice model (VPM [Valuing people with dementia and those who care for them (V); treating people as Individuals (I); looking at the world from the Perspective of the person with dementia (P); and a positive Social environment in which the person living with dementia […]