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Physical activity over the life course and its association with cognitive performance and impairment in old age


Middleton, Laura E., Barnes, Deborah E., Lui, Li-Yung, Yaffe, Kristine


Journal Of The American Geriatrics Society, Volume: 58, No.: 7, Pages.: 1322-1326

Year of Publication



Objective: To determine how physical activity at various ages over the life course is associated with cognitive impairment in late life.; Design: Cross-sectional study.; Setting: Four U.S. sites.; Participants: Nine thousand three hundred forty-four women aged 65 and older (mean 71.6) who self-reported teenage, age 30, age 50, and late-life physical activity.; Measurements: Logistic regression was used to determine the association between physical activity status at each age and likelihood of cognitive impairment (modified Mini-Mental State Examination (mMMSE) score >1.5 standard deviations below the mean, mMMSE score

Bibtex Citation

@article{Middleton_2010, doi = {10.1111/j.1532-5415.2010.02903.x}, url = {}, year = 2010, month = {jun}, publisher = {Wiley-Blackwell}, volume = {58}, number = {7}, pages = {1322--1326}, author = {Laura E. Middleton and Deborah E. Barnes and Li-Yung Lui and Kristine Yaffe}, title = {Physical Activity Over the Life Course and Its Association with Cognitive Performance and Impairment in Old Age}, journal = {Journal of the American Geriatrics Society} }


adolescent, adult, age factors, aged, cognition disorders, epidemiology, exercise, female, health behavior, humans, life style, logistic models, middle aged, motor activity, prevalence, psychology, united states

Countries of Study


Types of Dementia

Mild Cognitive Impairment (MCI)

Types of Study


Type of Outcomes


Type of Interventions

Risk Factor Modification

Risk Factor Modifications

General population health promotion