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Individual Cognitive Stimulation Therapy for dementia (iCST): study protocol for a randomized controlled trial


Orrell, Martin, Yates, Lauren A., Burns, Alistair, Russell, Ian, Woods, Robert T, Hoare, Zoe, Moniz-Cook, Esme, Henderson, Catherine, Knapp, Martin, Spector, Aimee, Orgeta, Vasiliki


Trials, Volume: 13, Pages.: 172-172

Year of Publication



Background: Improving the quality of care for people with dementia and their carers has become a national priority in many countries. Cognitive Stimulation Therapy (CST) groups can be beneficial in improving cognition and quality of life for people with dementia. The aim of the current study is to develop and evaluate a home-based individual Cognitive Stimulation Therapy (iCST) programme for people with dementia which can be delivered by their family carer.; Methods: This multi-centre, pragmatic randomised controlled trial (RCT) will compare the effectiveness and cost-effectiveness of iCST for people with dementia with a treatment as usual control group. The intervention consists of iCST sessions delivered by a carer for 30 minutes, 3 times a week over 25 weeks.For people with dementia the primary outcome measures are cognition assessed by the ADAS-Cog, and quality of life assessed by QoL-AD. For carers, quality of life using the SF-12 is the primary outcome measure. Using a 5% significance level, comparison of 306 participants will yield 80% power to detect an effect size of 0.35 for cognition as measured by the ADAS-Cog, and quality of life as measured by the QoL-AD. Quality of life for the carer will be measured using the SF-12. The trial will include a cost-effectiveness analysis from a public sector perspective.; Discussion: The UK Department of Health has recently stressed that improving access to psychological therapies is a national priority, but many people with dementia are unable to access psychological interventions. The development of a home-based individual version of CST will provide an easy to use, widely available therapy package that will be evaluated for effectiveness and cost-effectiveness in a multi centre RCT.;

Bibtex Citation

@article{Orrell_2012, doi = {10.1186/1745-6215-13-172}, url = {}, year = 2012, month = {sep}, publisher = {Springer Nature}, volume = {13}, number = {1}, author = {Martin Orrell and Lauren A Yates and Alistair Burns and Ian Russell and Robert T Woods and Zoe Hoare and Esme Moniz-Cook and Catherine Henderson and Martin Knapp and Aimee Spector and Vasiliki Orgeta}, title = {Individual Cognitive Stimulation Therapy for dementia ({iCST}): study protocol for a randomized controlled trial}, journal = {Trials} }


clinical protocols, cognitive therapy, dementia, humans, outcome assessment (health care), patient compliance, random allocation, sample size, therapy

Countries of Study


Types of Dementia

Dementia (general / unspecified)

Types of Study

Randomised Controlled Trial

Type of Outcomes

Cognition, Quality of Life of Carer, Quality of Life of Person With Dementia


Extra Care Housing

Type of Interventions

Non-pharmacological Treatment

Non-Pharmaceutical Interventions

Adult safeguarding and abuse detection/prevention