This site uses cookies to measure how you use the website so it can be updated and improved based on your needs and also uses cookies to help remember the notifications you’ve seen, like this one, so that we don’t show them to you again. If you could also tell us a little bit about yourself, this information will help us understand how we can support you better and make this site even easier for you to use and navigate.

Evaluation of a home-based exercise program in the treatment of Alzheimer’s disease: the Maximizing Independence in Dementia (MIND) study

Authors

Steinberg, Martin, Leoutsakos, Jeannie-Marie Sheppard, Podewils, Laura Jean, Lyketsos, C. G.

Journal

International Journal Of Geriatric Psychiatry, Volume: 24, No.: 7, Pages.: 680-685

Year of Publication

2009

Abstract

Objective: To determine the feasibility and efficacy of a home-based exercise intervention program to improve the functional performance of patients with Alzheimer’s Disease (AD).; Methods: Twenty-seven home-dwelling patients with AD were randomized to either an exercise intervention program delivered by their caregivers or a home safety assessment control. Measures of functional performance (primary), cognition, neuropsychiatric symptoms, quality of life and caregiver burden (secondary) were obtained at baseline and at 6 and 12 weeks following randomization. For each outcome measure, intent-to-treat analyses using linear random effects models were performed. Feasibility and adverse events were also assessed.; Results: Adherence to the exercise program was good. On the primary outcomes (functional performance) patients in the exercise group demonstrated a trend for improved performance on measures of hand function and lower extremity strength. On secondary outcome measures, trends toward worse depression and lower quality of life ratings were noted.; Conclusions: The physical exercise intervention developed for the study, delivered by caregivers to home-dwelling patients with AD, was feasible and was associated with a trend for improved functional performance in this group of frail patients. Given the limited efficacy to date of pharmacotherapies for AD, further study of exercise intervention, in a variety of care setting, is warranted.;

Bibtex Citation

@article{Steinberg_2009, doi = {10.1002/gps.2175}, url = {http://dx.doi.org/10.1002/gps.2175}, year = 2009, month = {jul}, publisher = {Wiley-Blackwell}, volume = {24}, number = {7}, pages = {680--685}, author = {Martin Steinberg and Jeannie-Marie Sheppard Leoutsakos and Laura Jean Podewils and C. G. Lyketsos}, title = {Evaluation of a home-based exercise program in the treatment of Alzheimer{textquotesingle}s disease: The Maximizing Independence in Dementia ({MIND}) study}, journal = {Int. J. Geriat. Psychiatry} }

Keywords

activities of daily living, aged, alzheimer disease, caregivers, exercise therapy, feasibility studies, female, geriatric assessment, home care services, humans, male, patient compliance, program evaluation, psychology, rehabilitation

Countries of Study

USA

Types of Dementia

Alzheimer’s Disease

Types of Study

Randomised Controlled Trial

Type of Outcomes

ADLs/IADLs, Behaviour, Carer Burden (instruments measuring burden), Cognition, Quality of Life of Person With Dementia

Settings

Extra Care Housing

Type of Interventions

Non-pharmacological Treatment

Non-Pharmaceutical Interventions

Exercise (inc. dancing)