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This database contains 125 studies, archived under the term: "study"

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Transcranial Magnetic Stimulation to Address Mild Cognitive Impairment in the Elderly: A Randomized Controlled Study
Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique with potential to improve memory. Mild cognitive impairment (MCI), which still lacks a specific therapy, is a clinical syndrome associated with increased risk of dementia. This study aims to assess the effects of high-frequency repetitive TMS (HF rTMS) on everyday memory of the elderly with […]

Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia
The aim of this study was to investigate the clinical effect of western medicine therapy assisted by Ginkgo biloba tablets (GBT) in patients with vascular cognitive impairment with no dementia (VCIND). Eighty patients with VCIND were randomly divided into two groups: the conventional treatment group (control group) and the combined treatment group. The conventional treatment […]

Quality of life and Alzheimer’s disease: The influence of participation in a rehabilitation center
Quality of life is seldom explored in evaluations of therapeutic interventions in Alzheimer’s disease. Objective: To verify whether participation in a cognitive and functional rehabilitation program improves quality of life (QOL) among Alzheimer’s disease (AD) patients. Methods: 19 AD patients participated in this study, 12 of whom attended 24 multi-professional intervention sessions—the experimental group—whereas the […]

Decreased self-reported cognitive failures after memory training
In recent years, attention has been focused on investigating the effectiveness of composite memory intervention programs with different age and diagnostics groups. The goal of this study was to measure changes in cognitive lapses by Cognitive Failure Questionnaire (CFQ) in a large trained, dementia free group (Mini-Mental State Examination [MMSE] > 26). The CFQ was […]

Family oversight and the quality of nursing home care for residents with advanced dementia
Background: The quality of nursing home (NH) care for residents with advanced dementia has been described as suboptimal. One relatively understudied factor in the provision of NH care is the role of private oversight and monitoring by family members and friends. Objective: To examine the association between private oversight and the quality of end-of-life care […]

Examination of a psychoeducational intervention and a respite grant in relieving psychosocial stressors associated with being an Alzheimer’s caregiver
Alzheimer’s disease can be particularly devastating to those who are caring for their loved one with the condition. There have been recent calls for the tailoring of caregiving interventions to examine outcome differences between groups of caregivers and the reporting of effectiveness via longitudinal and specific outcomes. The purpose of this study was to examine […]

No effect of donepezil on striatal dopamine release in mild to moderate Alzheimer’s disease
Objective: Work in experimental animals suggests that an interaction with dopaminergic networks might explain some of the therapeutic effects of the cholinesterase inhibitor class of drugs. This study aimed to test whether acute (single 5 mg) or 4–8 weeks (5–10 mg) of treatment with oral donepezil would elicit measurable striatal dopamine (DA) release in patients […]

Reducción del malestar psicológico y de la sobrecarga en familiares cuidadores de enfermos de Alzheimer mediante la aplicación de un programa de entrenamiento en mindfulness (conciencia plena). = Reducing psychological discomfort and overload in Alzheimer’s family caregivers through a mindfulness meditation program
Introduction: This study analyzes the effects that a mindfulness development meditation program has on psychological discomfort and overload in main family caregivers of Alzheimer dementia patients. Material and methods: A quasi-experimental (group comparison) design with pretest/post-test/follow-up measurements was employed in an experimental and a control group. The evaluation instruments used were the SCL-90-R Questionnaire and […]

Vitamins B₁₂, B₆, and folic acid for cognition in older men
[Correction Notice: An erratum for this article was reported in Vol 77(8) of Neurology (see record [rid]2011-21984-022[/rid]). In the original article, the daily dose of vitamin B12 used in the trial was reported as 400 μg, but it should have been 500 μg.] Objective: To investigate whether supplementing older men with vitamins B12, B6, and […]

The Computerized Self Test (CST): An interactive, internet accessible cognitive screening test for dementia
The computer self test (CST) is an interactive, internet-based instrument designed to assess functional cognitive domains impaired by Alzheimer’s disease (AD) and mild cognitive impairment (MCI). This study consisted of 215 total subjects with a mean age of 75.24. The 84 cognitively impaired patients (excluding patients diagnosed as MCI) met all criteria set forth by […]

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