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This database contains 32 studies, archived under the term: "Purpose"

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Examination of a psychoeducational intervention and a respite grant in relieving psychosocial stressors associated with being an Alzheimer’s caregiver
Alzheimer’s disease can be particularly devastating to those who are caring for their loved one with the condition. There have been recent calls for the tailoring of caregiving interventions to examine outcome differences between groups of caregivers and the reporting of effectiveness via longitudinal and specific outcomes. The purpose of this study was to examine […]

Effects of an interactive video game (Nintendo WiiTM) on older women with mild cognitive impairment
Older adults with a cognitive impairment in residential care settings are often found to be inactive throughout the day. Participation in video games holds promise for these individuals; however, effects of video games played by older adults have not been studied consistently and the few studies conducted have yielded mixed results. The purpose of this […]

Impact of TimeSlips, a creative expression intervention program, on nursing home residents with dementia and their caregivers
Purpose: Creative expression (CE) programs are emerging interventions to improve the quality of care and life of persons with dementia (PWDs) in long-term care settings. However, limited empirical evidence exists to support the effectiveness of these programs. Here, we report the findings from an assessment of the impact of TimeSlips (TS), a group storytelling program […]

Translating the REACH caregiver intervention for use by area agency on aging personnel: The REACH OUT Program
Purpose: The aim of this study was to translate the evidence-based Resources for Enhancing Alzheimer’s Caregiver Health (REACH) II intervention for use in 4 Area Agencies on Aging (AAAs). A secondary aim was to examine possible moderators of treatment outcome. Design and Methods: We used a quasi-experimental pre-post treatment design with no control group. A […]

A community-based approach to trials of aerobic exercise in aging and Alzheimer’s disease
The benefits of exercise for aging have received considerable attention in both the popular and academic press. The putative benefits of exercise for maximizing cognitive function and supporting brain health have great potential for combating Alzheimer’s disease (AD). Aerobic exercise offers a low-cost, low-risk intervention that is widely available and may have disease modifying effects. […]

Working memory capacity and its relation to stroop interference and facilitation effects in individuals with mild cognitive impairment
Purpose: The purposes of the study were to investigate (a) the task-specific differences in short-term memory (STM) and working memory capacity (WMC) in individuals with mild cognitive impairment (MCI) and normal elderly adults (NEAs), (b) the Stroop interference and facilitation effects, and (c) the relationship of STM and WMC to the Stroop effects.; Method: Thirty-two […]

Effectiveness of a condensed protocol for disclosing APOE genotype and providing risk education for Alzheimer disease
Purpose: Brief, effective models of patient genetic education are needed for common, complex diseases. Using Alzheimer disease as a model, we compared participants’ risk knowledge and recall in extended versus condensed education protocols.; Methods: A four-site randomized clinical trial enrolled 280 first-degree relatives of individuals with Alzheimer disease (mean age = 58 years, 71% female); […]

Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people
Background: Curcumin extracts of turmeric are proposed to produce health benefits. To date, human intervention studies have focused mainly on people with existing health problems given high doses of poorly absorbed curcumin. The purpose of the current study was to check whether in healthy people, a low dose of a lipidated curcumin extract could alter […]

Physical therapy in Huntington’s disease–toward objective assessments?
Background and Purpose: Physical therapy is recommended for the treatment of Huntington’s disease, but reliable studies investigating its efficacy are almost non-existent. This may in part be due to the lack of suitable outcome measures. Therefore, we investigated the applicability of novel quantitative and objective assessments of motor dysfunction in the evaluation of physical therapy […]

A randomized feasibility study of a 12-week community-based exercise program for people with Huntington’s disease
BACKGROUND AND PURPOSE: The beneficial role of exercise as a treatment approach in Huntington’s disease (HD) has support from both preclinical work and small-scale studies; however, there have been no controlled studies of gym-based exercise in people with HD. This phase 2 randomized trial (ISRCTN 59910670) assessed feasibility, safety, acceptability, and benefit of a structured […]

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