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Effects of multicomponent exercise on spatial-temporal gait parameters among the elderly with amnestic mild cognitive impairment (aMCI): preliminary results from a randomized controlled trial (RCT)
Doi, Takehiko,
Makizako, Hyuma,
Shimada, Hiroyuki,
Yoshida, Daisuke,
Tsutsumimoto, Kota,
Sawa, Ryuichi,
Misu, Shogo,
Suzuki, Takao
Exercise training has been shown to increase physical function in the elderly. However, the effects of exercise on elderly individuals with amnestic aMCI are unclear. The aim of...
Long-term safety and efficacy of donepezil in patients with dementia with Lewy bodies: results from a 52-week, open-label, multicenter extension study
Ikeda, Manabu,
Mori, Etsuro,
Kosaka, Kenji,
Iseki, Eizo,
Hashimoto, Mamoru,
Matsukawa, Noriyuki,
Matsuo, Kazutaka,
Nakagawa, Masaki
...was unlikely to appear.; Conclusion: The long-term administration of donepezil at 5 mg/day was well tolerated in patients with DLB and is expected to exhibit lasting effects, improving impaired cognitive...
Physical activity attenuates age-related biomarker alterations in preclinical AD
Okonkwo, O. C.,
Schultz, S. A.,
Oh, J. M.,
Larson, J.,
Edwards, D.,
Cook, D.,
Koscik, R.,
Gallagher, C. L.,
Dowling, N. M.,
Carlsson, C. M.,
Bendlin, B. B.,
LaRue, A.,
Rowley, H. A.,
Christian, B. T.,
Asthana, S.,
Hermann, B. P.,
Johnson, S. C.,
Sager, M. A.
...whether midlife participation in structured physical exercise forestalls the development of AD and related disorders in later life. (PsycINFO Database Record (c) 2015 APA, all rights reserved). (journal abstract)...
Efficacy and tolerability of risperidone, yokukansan, and fluvoxamine for the treatment of behavioral and psychological symptoms of dementia: a blinded, randomized trial
Teranishi, Mika,
Kurita, Masatake,
Nishino, Satoshi,
Takeyoshi, Kenji,
Numata, Yukio,
Sato, Tadahiro,
Tateno, Amane,
Okubo, Yoshiro
...its items. Secondary outcome measures were cognitive function measured by Mini-Mental State Examination and daily life function measured by Functional Independence Measure (FIM). Neurological adverse effects were measured by the...
Cognitive dysfunction in HIV patients despite long-standing suppression of viremia
Simioni, Samanta,
Cavassini, Matthias,
Annoni, Jean-Marie,
Rimbault Abraham, Aline,
Bourquin, Isabelle,
Schiffer, Véronique,
Calmy, Alexandra,
Chave, Jean-Philippe,
Giacobini, Ezio,
Hirschel, Bernard,
Du Pasquier, Renaud A.
...daily life (asymptomatic neurocognitive impairment) is the most frequent subtype observed. In this population, the HIV dementia scale with a cutoff of 14 points or less seems to provide a...
Impact of smoking on cognitive decline in early old age: the Whitehall II cohort study
Sabia, Séverine,
Elbaz, Alexis,
Dugravot, Aline,
Head, Jenny,
Shipley, Martin,
Hagger-Johnson, Gareth,
Kivimaki, Mika,
Singh-Manoux, Archana
...Context: Smoking is a possible risk factor for dementia, although its impact may have been underestimated in elderly populations because of the shorter life span of smokers.; Objective: To...
Physical activity and cognitive functioning in the oldest old: Within- and between-person cognitive activity and psychosocial mediators
Robitaille, Annie,
Muniz, Graciela,
Lindwall, Magnus,
Piccinin, Andrea M.,
Hoffman, Lesa,
Johansson, Boo,
Hofer, Scott M.
The current study examines the role of social contact intensity, cognitive activity, and depressive symptoms as within- and between-person mediators for the relationships between physical activity and cognitive...