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Neuropsychological criteria for mild cognitive impairment improves diagnostic precision, biomarker associations, and progression rates
Bondi, Mark W.,
Edmonds, Emily C.,
Jak, Amy J.,
Clark, Lindsay R.,
Delano-Wood, Lisa,
McDonald, Carrie R.,
Nation, Daniel A.,
Libon, David J.,
Au, Rhoda,
Galasko, Douglas,
Salmon, David P.
...method did not produce a subtype that performed within normal limits on the cognitive testing, unlike the conventional diagnostic method. Findings support the need for refinement of MCI diagnoses to...
A randomized controlled trial to examine the effectiveness of case management model for community dwelling older persons with mild dementia in Hong Kong
Lam, Linda C. W.,
Lee, Jenny S. W.,
Chung, Jenny C. C.,
Lau, Anna,
Woo, Jean,
Kwok, Timothy C. Y.
...> 0.05).; Conclusion: Case management for Chinese persons with mild dementia outpatients did not show significant effects in reducing caregiver burden, but encouraged family caregivers to seek external support.;...
Group therapy for patients with mild cognitive impairment and their significant others: Results of a waiting-list controlled trial
Banningh, Liesbeth W. A. Joosten-Weyn,
Prins, Judith B.,
Vernooij-Dassen, Myrra J. F. J.,
Wijnen, Hugo H.,
Rikkert, Marcel G. M. Olde,
Kessels, Roy P. C.
Background: Patients with mild cognitive impairment (MCI) have to deal with an uncertain prognosis and also face a multitude of memory-related problems and psychosocial consequences. A newly developed...
Effect of TTP488 in patients with mild to moderate Alzheimer’s disease
Burstein, Aaron H,
Grimes, Imogene,
Galasko, Douglas R,
Aisen, Paul S,
Sabbagh, Marwan,
Mjalli, Adnan MM
...relative to placebo was evident at 46.8-167.0 ng/mL.; Conclusions: Results of these analyses support further investigation of 5 mg/day in future Phase 3 trials in patients with mild AD.;...
Evidence for neurocognitive plasticity in at-risk older adults: the experience corps program
Carlson, M. C.,
Erickson, K. I.,
Kramer, A. F.,
Voss, M. W.,
Bolea, N.,
Mielke, M.,
McGill, S.,
Rebok, G. W.,
Seeman, T.,
Fried, L. P.
...for use-dependent brain plasticity in later life, and, that interventions designed to promote health and function through everyday activity may enhance plasticity in key regions that support executive function.;...
Mental and physical activities delay cognitive decline in older persons with dementia
Cheng, Sheung-Tak,
Chow, Pizza K.,
Song, You-Qiang,
Yu, Edwin C.S.,
Chan, Alfred C.M.,
Lee, Tatia M.C.,
Lam, John H.M.
Objectives: To examine the effects of cognitive stimulation (mahjong) and physical exercise (tai chi [TC]) on cognitive performance in persons with dementia.; Design: Cluster-randomized open-label controlled design.; Setting:...