This database contains 32 studies, archived under the term: "young adult"
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Additional use of Aβ₄₂/Aβ₄₀ ratio with cerebrospinal fluid biomarkers P-tau and Aβ₄₂ increases the level of evidence of Alzheimer’s disease pathophysiological process in routine practice
Sauvée, Mathilde,
DidierLaurent, Guerric,
Latarche, Clotilde,
Escanyé, Marie-Christine,
Olivier, Jean-Luc,
Malaplate-Armand, Catherine
Background: Cerebrospinal fluid (CSF) biomarkers have recently been included in the criteria for the diagnosis of Alzheimer’s disease (AD). Since interpretation of CSF profile requires the combination of three parameters, biological data are not always conclusive and isolated elevation of phosphorylated tau (P-tau) or reduction of amyloid-β (Aβ)42 alone can be observed. In these cases, […]
Maintenance of health and relief for caregivers of elderly with dementia by using “initial case management”: experiences from the Lighthouse Project on Dementia, Ulm, ULTDEM-study
Lukas, A.,
Kilian, R.,
Hay, B.,
Muche, R.,
von Arnim, C.A.F.,
Otto, M.,
Riepe, M.,
Jamour, M.,
Denkinger, M.D.,
Nikolaus, T.
Background: When facing the well-known demographic development with an increasing number of people suffering from dementia, there is a need of programmes to support nursing relatives and care at home. Many support services have been established in the past few years but they are rarely used by the relatives and the patients. The purpose of […]
Learning opportunities in a residential aged care facility: the role of supported placements for first-year nursing students
Lea, Emma,
Marlow, Annette,
Bramble, Marguerite,
Andrews, Sharon,
Crisp, Elaine,
Eccleston, Claire,
Mason, Ron,
Robinson, Andrew
The residential aged care sector is reportedly a less attractive career choice for nursing students than other sectors. Research shows that students are often fearful of working with residents with dementia when they are inadequately supported on clinical placements by aged care staff. Thirty first-year nursing students attended a 2-week placement in one of two […]
Comparison of two analytical platforms for the clinical qualification of Alzheimer’s disease biomarkers in pathologically-confirmed dementia
Le Bastard, Nathalie,
Coart, Els,
Vanderstichele, Hugo,
Vanmechelen, Eugeen,
Martin, Jean-Jacques,
Engelborghs, Sebastiaan
Combined analysis of the Alzheimer’s disease (AD) biomarkers amyloid-β(1-42) (Aβ(1-42)), total tau (T-tau), and hyperphosphorylated tau (P-tau(181P)) in cerebrospinal fluid (CSF) reduces the uncertainty associated with clinical dementia diagnosis. The present study evaluated the diagnostic accuracy of the CSF biomarker concentrations obtained with a multi-analyte Luminex assay (INNO-BIA AlzBio3) in comparison to single-analyte ELISA tests […]
Irritable bowel syndrome correlates with increased risk of Parkinson’s disease in Taiwan
This study investigated whether an association exists between irritable bowel syndrome (IBS) and the risk of Parkinson’s disease. This is a retrospective cohort study using the dataset of the Taiwan National Health Insurance Program from 2000 to 2010. We identified 23,875 patients (aged 20 years or older) with newly diagnosed IBS as the IBS group […]