This database contains 108 studies, archived under the term: "statistics & numerical data"
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DHEA and cognition in HIV-positive patients with non-major depression
Background: Dihydroepiandrosterone (DHEA) has been investigated for its potential role in improving cognition in a number of patient populations. Treatment options are limited for HIV-associated neurocognitive disorders.; Objective: The authors tested the effect of DHEA administration on the cognitive functioning of HIV-positive subjects with non-major depression.; Method: The neuropsychological testing data for 60 HIV-positive patients […]
Study protocol: EXERcise and cognition in sedentary adults with early-ONset dementia (EXERCISE-ON)
Hooghiemstra, Astrid M.,
Eggermont, Laura H.P.,
Scheltens, Philip,
van der Flier, Wiesje M.,
Bakker, Jet,
de Greef, Mathieu H. G.,
Koppe, Peter A.,
Scherder, Erik J.A.
Background: Although the development of early-onset dementia is a radical and invalidating experience for both patient and family there are hardly any non-pharmacological studies that focus on this group of patients. One type of a non-pharmacological intervention that appears to have a beneficial effect on cognition in older persons without dementia and older persons at […]
Effect of second-generation antipsychotics on caregiver burden in Alzheimer’s disease
Mohamed, Somaia,
Rosenheck, Robert,
Lyketsos, Constantine G.,
Kaczynski, Richard,
Sultzer, David L.,
Schneider, Lon S.
Background: Alzheimer’s disease (AD) imposes a severe burden upon patients and their caregivers. Severity of psychiatric symptoms and behavioral disturbances is an important determinant of caregivers’ experience of burden. These symptoms may be improved with atypical antipsychotic treatment.; Objective: Data from the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer’s Disease (CATIE-AD) trial were used to evaluate […]
Leisure activities alleviate depressive symptoms in nursing home residents with very mild or mild dementia
Objectives: : To examine whether leisure activities can alleviate depressive symptoms among nursing home residents with very mild to mild dementia.; Methods: : A cluster-randomized open-label controlled design. Thirty-six residents with at least moderate depressive symptoms were randomized by home into three conditions-mahjong (a.k.a. mah-jongg), tai chi, and handicrafts (placebo). Activities were conducted three times […]
The effect of stimulation therapy and donepezil on cognitive function in Alzheimer’s disease. A community based RCT with a two-by-two factorial design
Andersen, Fred,
Viitanen, Matti,
Halvorsen, Dag S.,
Straume, Bjørn,
Wilsgaard, Tom,
Engstad, Torgeir A.
Background: Progressive neurodegeneration in Alzheimer’s disease (AD) induces cognitive deterioration, and there is controversy regarding the optimal treatment strategy in early AD. Stimulation therapy, including physical exercise and cholinesterase inhibitors are both reported to postpone cognitive deterioration in separate studies. We aimed to study the effect of stimulation therapy and the additional effect of donepezil […]
Two-year effects of an interdisciplinary intervention on recovery following hip fracture in older Taiwanese with cognitive impairment
Shyu, Yea-Ing L.,
Tsai, Wen-Che,
Chen, Min-Chi,
Liang, Jersey,
Cheng, Huey-Shinn,
Wu, Chi-Chuan,
Su, Juin-Yih,
Chou, Shih-Wei
Objective: This article aims to evaluate the long-term effects of an interdisciplinary intervention program on cognitively impaired older persons after hip fracture in Taiwan.; Methods: Of 160 subjects randomly assigned to control (n = 81) and intervention (n = 79) groups, 24 (29.6%) and 27 (34.2%) were cognitively impaired in the control and intervention groups, […]
Healing gardens and cognitive behavioral units in the management of Alzheimer’s disease patients: the Nancy experience
Rivasseau Jonveaux, T.,
Batt, M.,
Fescharek, R.,
Benetos, A.,
Trognon, A.,
Bah Chuzeville, S.,
Pop, A.,
Jacob, C.,
Yzoard, M.,
Demarche, L.,
Soulon, L.,
Malerba, G.,
Bouvel, B.
The French Alzheimer Plan 2008-2012 anticipates the implementation of new Units specialized in cognitive rehabilitation and psycho-behavioral therapy of Alzheimer’s disease (AD) patients. Conceived for AD and other dementia patients of all ages, their objectives are to propose a cognitive rehabilitation program, to prevent or treat psycho-behavioral crises, and to provide support and educational therapy […]