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This database contains 61 studies, archived under the term: "reproducibility of results"

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Computer-assisted system for diagnosis of Alzheimer disease using data base- independent estimation and fluorodeoxyglucose- positron-emission tomography and 3D-stereotactic surface projection

Background and Purpose: Recently, voxel-based statistical parametric images have been developed as additional diagnostic tools for AD. However these methods require the generation of a data base of healthy brain images. The purpose of this study was to produce and evaluate an automatic method using a data base-independent estimation system for the diagnosis of mild […]

Validation of the interRAI Cognitive Performance Scale against independent clinical diagnosis and the Mini-Mental State Examination in older hospitalized patients

Objective: To compare the diagnostic accuracy of the interRAI Acute Care (AC) Cognitive Performance Scale (CPS2) and the Mini-Mental State Examination (MMSE), against independent clinical diagnosis for detecting dementia in older hospitalized patients.; Design, Setting, and Participants: The study was part of a prospective observational cohort study of patients aged ≥70 years admitted to four […]

Neuroimaging predictors of brain amyloidosis in mild cognitive impairment

Objective: To identify a neuroimaging signature predictive of brain amyloidosis as a screening tool to identify individuals with mild cognitive impairment (MCI) that are most likely to have high levels of brain amyloidosis or to be amyloid-free.; Methods: The prediction model cohort included 62 MCI subjects screened with structural magnetic resonance imaging (MRI) and (11) […]

Reliability and validity of A Quick Test of Cognitive Speed for detecting early-stage dementia in elderly Japanese

Aim: The aim of this study was to evaluate the reliability and validity of A Quick Test of Cognitive Speed (AQT) for detecting early-stage dementia in the elderly Japanese population.; Methods: A total of 280 clinical participants (180 with mild Alzheimer’s disease, 43 with amnestic mild cognitive impairment, 32 with non-amnestic mild cognitive impairment and […]

The Nottingham Health Profile: a feasible questionnaire for nursing home residents?

Background: The Nottingham Health Profile (NHP) assesses perceived emotional, social, and physical health problems and the extent to which such problems affect daily activities. The objective of our study was to determine the feasibility of the NHP for nursing home residents.; Methods: A prospective multicenter observational study was conducted in 11 nursing homes from April […]

Reliability and validity of the Norwegian version of the Brief Agitation Rating Scale (BARS) in dementia

Objective: To examine the test-retest reliability and validity of the Norwegian Brief Agitation Rating Scale (BARS), a short form of the Cohen-Mansfield Agitation Inventory (CMAI) assessing the frequency of agitation in dementia.; Methods: We investigated the internal consistency, test-retest reliability and the validity of BARS. In the validity study, we compared the BARS scores with […]

Effects of age, gender, education and race on two tests of language ability in community-based older adults

Background: Neuropsychological tests, including tests of language ability, are frequently used to differentiate normal from pathological cognitive aging. However, language can be particularly difficult to assess in a standardized manner in cross-cultural studies and in patients from different educational and cultural backgrounds. This study examined the effects of age, gender, education and race on performance […]

Psychometric evaluation of the Swedish version of the Person-Centered Care Assessment Tool (P-CAT)

Background: Person-centered care is a multidimensional concept describing good care, especially within aged care and care for people with dementia. Research studies evaluating person-centered care interventions seldom use direct measurement of levels of person-centeredness. Existing scales that measure person-centeredness need further testing. This study evaluated the psychometric properties of the Swedish version of the Person-Centered […]

Longitudinal progression of cognitive decline correlates with changes in the spatial pattern of brain 18F-FDG PET

Unlabelled: Evaluating the symptomatic progression of mild cognitive impairment (MCI) caused by Alzheimer disease (AD) is practically accomplished by tracking performance on cognitive tasks, such as the Alzheimer Disease Assessment Scale’s cognitive subscale (ADAS_cog), the Mini-Mental Status Examination (MMSE), and the Functional Activities Questionnaire (FAQ). The longitudinal relationships between cognitive decline and metabolic function as […]

Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI

The close correlation between abnormally low pre-mortem cerebrospinal fluid (CSF) concentrations of amyloid-β1-42 (Aβ(1-42)) and plaque burden measured by amyloid imaging as well as between pathologically increased levels of CSF tau and the extent of neurodegeneration measured by MRI has led to growing interest in using these biomarkers to predict the presence of AD plaque […]

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