This database contains 17 studies, archived under the term: "regression analysis"
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Non-pharmacological, multicomponent group therapy in patients with degenerative dementia: a 12-month randomizied, controlled trial
Graessel, Elmar,
Stemmer, Renate,
Eichenseer, Birgit,
Pickel, Sabine,
Donath, Carolin,
Kornhuber, Johannes,
Luttenberger, Katharina
Background: Currently available pharmacological and non-pharmacological treatments have shown only modest effects in slowing the progression of dementia. Our objective was to assess the impact of a long-term non-pharmacological group intervention on cognitive function in dementia patients and on their ability to carry out activities of daily living compared to a control group receiving the […]
Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease
Penner, Jacob,
Rupsingh, Raul,
Smith, Matthew,
Wells, Jennie L.,
Borrie, Michael J.,
Bartha, Robert
Galantamine is a cholinesterase inhibitor and allosteric potentiating ligand modulating presynaptic nicotinic acetylcholine receptors that is used in the treatment of Alzheimer disease (AD). The purpose of this study was to determine if galantamine treatment would result in detectable hippocampal metabolite changes that correlated with changes in cognition, as measured by the Mini-Mental State Examination […]
Relationship between baseline glycemic control and cognitive function in individuals with type 2 diabetes and other cardiovascular risk factors: the action to control cardiovascular risk in diabetes-memory in diabetes (ACCORD-MIND) trial
Cukierman-Yaffe, Tali,
Gerstein, Hertzel C.,
Williamson, Jeff D.,
Lazar, Ronald M.,
Lovato, Laura,
Miller, Michael E.,
Coker, Laura H.,
Murray, Anne,
Sullivan, Mark D.,
Marcovina, Santica M.,
Launer, Lenore J.
Objective: Diabetes is associated with cognitive decline and dementia. However, the relationship between the degree of hyperglycemia and cognitive status remains unclear. This was explored using baseline cognitive measures collected in the ongoing Memory in Diabetes (MIND) substudy of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.; Research Design and Methods: The relationship […]
Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative
Carmichael, Owen,
Schwarz, Christopher,
Drucker, David,
Fletcher, Evan,
Harvey, Danielle,
Beckett, Laurel,
Jack, Clifford R., Jr.,
Weiner, Michael,
DeCarli, Charles
Objective: To evaluate relationships between magnetic resonance imaging (MRI)-based measures of white matter hyperintensities (WMHs), measured at baseline and longitudinally, and 1-year cognitive decline using a large convenience sample in a clinical trial design with a relatively mild profile of cardiovascular risk factors.; Design: Convenience sample in a clinical trial design.; Subjects: A total of […]
Midlife cardiovascular risk factors and late cognitive impairment
Virta, Jyri J.,
Heikkilä, Kauko,
Perola, Markus,
Koskenvuo, Markku,
Räihä, Ismo,
Rinne, Juha O.,
Kaprio, Jaakko
Cardiovascular risk factors increase the risk of dementia in later life. The aims of the current study were to assess the effect of multiple midlife cardiovascular risk factors on the risk of cognitive impairment in later life, and to assess the validity of the previously suggested CAIDE Study risk score predicting dementia risk 20 years later. […]
Comparison of the memory performance index with standard neuropsychological measures of cognition
The Mild Cognitive Impairment Screen (MCIS) is a computer-based cognitive assessment designed for clinical and research use in detecting amnestic mild cognitive impairment (aMCI). Performance on the MCIS is reported as the Memory Performance Index (MPI). However, the comparability between the MPI and traditional neuropsychological tests in detecting aMCI, and in differentiating it from Alzheimer’s […]