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This database contains 12 studies, archived under the term: "reaction time"

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A proteomics study reveals a predominant change in MaoB expression in platelets of healthy volunteers after high protein meat diet: relationship to the methylation cycle
Studies investigating the impact of high meat intake on cognition have yielded contradictory results as some show improved cognitive performance, whereas others report an increase of risk factors for dementia. However, few studies were designed to directly assess the effect of a high protein (HP) diet on both cognitive performance and corresponding biochemical parameters. A […]

Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial
Objective: To preliminarily assess the safety and efficacy of transdermal nicotine therapy on cognitive performance and clinical status in subjects with mild cognitive impairment (MCI).; Methods: Nonsmoking subjects with amnestic MCI were randomized to transdermal nicotine (15 mg per day or placebo) for 6 months. Primary outcome variables were attentional improvement assessed with Connors Continuous […]

Training of attentional control in mild cognitive impairment with executive deficits: results from a double-blind randomised controlled study
This study evaluated the efficacy of a cognitive intervention for attentional control in older adults with mild cognitive impairment (MCI) with an executive deficit. It also sought to verify if the benefits of training generalised to primary and secondary outcome measures. Participants (n = 24) were randomly assigned to a training programme or active control […]

Acute caffeine administration effect on brain activation patterns in mild cognitive impairment
Previous studies showed that acute caffeine administration enhances task-related brain activation in elderly individuals with preserved cognition. To explore the effects of this widely used agent on cognition and brain activation in early phases of cognitive decline, we performed a double-blinded, placebo-controlled functional magnetic resonance imaging (fMRI) study during an n-back working memory task in […]

Responders to ChEI treatment of Alzheimer’s disease show restitution of normal regional cortical activation
Clinical trials of cholinesterase inhibitor (ChEI) drugs, although generally reporting only minimal improvements in patients with Alzheimer’s disease (AD), indicate that a subgroup of patients may respond substantially to treatment. This study aimed to assess the clinically variable ChEI treatment effects in a group of patients with mild AD using a semantic association and an […]

Does auditory rhythmical cueing improve gait in people with Parkinson’s disease and cognitive impairment? A feasibility study
Gait and balance problems resulting from Parkinson’s disease (PD) are more common in people with PD and dementia (PDD), yet, it is unknown whether the benefits of cueing therapy for mobility generalize to them. We aimed to determine the feasibility and effectiveness of auditory cues to improve gait in PD and cognitive impairment (PD-CI). Nine […]

Visual hallucinations and altered visual information processing in Parkinson disease and dementia with Lewy bodies
Visual hallucinations (VHs) are common in dementia with Lewy bodies (DLB) and Parkinson’s disease with dementia (PDD), while auditory hallucinations are rare. To neurophysiologically investigate the pathophysiology of VHs in these disorders, we studied event-related potentials (ERPs) of DLB, PDD, and Alzheimer’s disease (AD) patients. We compared visual and auditory ERP latencies among PDD patients […]

Visual evoked potentials to pattern, motion and cognitive stimuli in Alzheimer’s disease
The aim of our study was to verify reported visual dysfunctions of patients with Alzheimer disease with the use of several variants of VEPs and visual ERPs and to learn whether these methods can be useful in diagnostics of AD. We tested 15 patients (6 women and 9 men, aged from 58 to 87) with […]

Effects of cholinesterase inhibitors on visual attention in drivers with Alzheimer disease
Objective: We conducted a combined observational cohort and case-control study in patients with Alzheimer disease (AD) to assess the effects of acetylcholinesterase inhibitor (ChEI) treatment on cognitive functions important for driving.; Methods: Performance of 24 outpatients with newly diagnosed (untreated) early-stage AD was compared before beginning ChEI (pre-ChEI) and after 3 months of therapy (post-ChEI) […]

Reliability and validity of A Quick Test of Cognitive Speed for detecting early-stage dementia in elderly Japanese
Aim: The aim of this study was to evaluate the reliability and validity of A Quick Test of Cognitive Speed (AQT) for detecting early-stage dementia in the elderly Japanese population.; Methods: A total of 280 clinical participants (180 with mild Alzheimer’s disease, 43 with amnestic mild cognitive impairment, 32 with non-amnestic mild cognitive impairment and […]

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