This database contains 67 studies, archived under the term: "outcome assessment (health care)"
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Individual Cognitive Stimulation Therapy for dementia (iCST): study protocol for a randomized controlled trial
Orrell, Martin,
Yates, Lauren A.,
Burns, Alistair,
Russell, Ian,
Woods, Robert T,
Hoare, Zoe,
Moniz-Cook, Esme,
Henderson, Catherine,
Knapp, Martin,
Spector, Aimee,
Orgeta, Vasiliki
Background: Improving the quality of care for people with dementia and their carers has become a national priority in many countries. Cognitive Stimulation Therapy (CST) groups can be beneficial in improving cognition and quality of life for people with dementia. The aim of the current study is to develop and evaluate a home-based individual Cognitive […]
Peer support for family carers of people with dementia, alone or in combination with group reminiscence in a factorial design: study protocol for a randomised controlled trial
Charlesworth, Georgina,
Burnell, Karen,
Beecham, Jennifer,
Hoare, Zoe,
Hoe, Juanita,
Wenborn, Jennifer,
Knapp, Martin,
Russell, Ian,
Woods, Bob,
Orrell, Martin
Background: Peer support interventions can improve carer wellbeing and interventions that engage both the carer and person with dementia can have significant mutual benefits. Existing research has been criticised for inadequate rigour of design or reporting. This paper describes the protocol for a complex trial that evaluates one-to-one peer support and a group reminiscence programme, […]
V-TIME: a treadmill training program augmented by virtual reality to decrease fall risk in older adults: study design of a randomized controlled trial
Mirelman, Anat,
Rochester, Lynn,
Reelick, Miriam,
Nieuwhof, Freek,
Pelosin, Elisa,
Abbruzzese, Giovanni,
Dockx, Kim,
Nieuwboer, Alice,
Hausdorff, Jeffrey M.
Background: Recent work has demonstrated that fall risk can be attributed to cognitive as well as motor deficits. Indeed, everyday walking in complex environments utilizes executive function, dual tasking, planning and scanning, all while walking forward. Pilot studies suggest that a multi-modal intervention that combines treadmill training to target motor function and a virtual reality […]
Life- and person-centred help in Mecklenburg-Western Pomerania, Germany (DelpHi): study protocol for a randomised controlled trial
Thyrian, Jochen René,
Fiß, Thomas,
Dreier, Adina,
Böwing, Georgia,
Angelow, Aniela,
Lueke, Sven,
Teipel, Stefan,
Fleßa, Steffen,
Grabe, Hans Jörgen,
Freyberger, Harald Jürgen,
Hoffmann, Wolfgang
Background: The provision of appropriate medical and nursing care for people with dementia is a major challenge for the healthcare system in Germany. New models of healthcare provision need to be developed, tested and implemented on the population level. Trials in which collaborative care for dementia in the primary care setting were studied have demonstrated […]
Alzheimer’s disease–input of vitamin D with mEmantine assay (AD-IDEA trial): study protocol for a randomized controlled trial
Annweiler, Cedric,
Fantino, Bruno,
Parot-Schinkel, Elsa,
Thiery, Samuel,
Gautier, Jennifer,
Beauchet, Olivier
Background: Current treatments for Alzheimer’s disease and related disorders (ADRD) are symptomatic and can only temporarily slow down ADRD. Future possibilities of care rely on multi-target drugs therapies that address simultaneously several pathophysiological processes leading to neurodegeneration. We hypothesized that the combination of memantine with vitamin D could be neuroprotective in ADRD, thereby limiting neuronal […]
Use of the Tailored Activities Program to reduce neuropsychiatric behaviors in dementia: an Australian protocol for a randomized trial to evaluate its effectiveness
O'Connor, C. M.,
Clemson, L.,
Brodaty, H.,
Jeon, Y. H.,
Mioshi, E.,
Gitlin, L. N.
Background: Behavioral and psychological symptoms of dementia (BPSD) are often considered to be the greatest challenge in dementia care, leading to increased healthcare costs, caregiver burden, and placement into care facilities. With potential for pharmacological intervention to exacerbate behaviors or even lead to mortality, the development and rigorous testing of non-pharmacological interventions is vital. A […]
Tailored educational intervention for primary care to improve the management of dementia: the EVIDEM-ED cluster randomized controlled trial
Wilcock, Jane,
Iliffe, Steve,
Griffin, Mark,
Jain, Priya,
Thuné-Boyle, Ingela,
Lefford, Frances,
Rapp, David
Background: Early diagnosis of dementia is important because this allows those with dementia and their families to engage support and plan ahead. However, dementia remains underdetected and suboptimally managed in general practice. Our objective was to test the effect of a workplace-based tailored educational intervention developed for general practice on the clinical management of people […]
Cognitive rehabilitation changes memory-related brain activity in people with Alzheimer disease
van Paasschen, J.,
Clare, L.,
Yuen, K. S. L.,
Woods, R. T.,
Evans, S. J.,
Parkinson, C. H.,
Rugg, M. D.,
Linden, D. E. J.
Background: People with Alzheimer disease (AD) are capable of new learning when cognitive support is provided, suggesting that there is plasticity even in a degenerating brain. However, it is unclear how a cognition-focused intervention operates on a neural level.; Objective: The present study examined the effects of cognitive rehabilitation (CR) on memory-related brain activation in […]
Decision-making and outcomes of feeding tube insertion: a five-state study
Teno, Joan M.,
Mitchell, Susan L.,
Kuo, Sylvia K.,
Gozalo, Pedro L.,
Rhodes, Ramona L.,
Lima, Julie C.,
Mor, Vincent
Objectives: To examine family member’s perceptions of decision-making and outcomes of feeding tubes.; Design: Mortality follow-back survey. Sample weights were used to account for oversampling and survey design. A multivariate model examined the association between feeding tube use and overall quality of care rating regarding the last week of life.; Setting: Nursing homes, hospitals, and […]