This database contains 366 studies, archived under the term: "methods"
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Decision-making and outcomes of feeding tube insertion: a five-state study
Teno, Joan M.,
Mitchell, Susan L.,
Kuo, Sylvia K.,
Gozalo, Pedro L.,
Rhodes, Ramona L.,
Lima, Julie C.,
Mor, Vincent
Objectives: To examine family member’s perceptions of decision-making and outcomes of feeding tubes.; Design: Mortality follow-back survey. Sample weights were used to account for oversampling and survey design. A multivariate model examined the association between feeding tube use and overall quality of care rating regarding the last week of life.; Setting: Nursing homes, hospitals, and […]
Multicenter stability of diffusion tensor imaging measures: a European clinical and physical phantom study
Teipel, Stefan J.,
Reuter, Sigrid,
Stieltjes, Bram,
Acosta-Cabronero, Julio,
Ernemann, Ulrike,
Fellgiebel, Andreas,
Filippi, Massimo,
Frisoni, Giovanni,
Hentschel, Frank,
Jessen, Frank,
Klöppel, Stefan,
Meindl, Thomas,
Pouwels, Petra J.W.,
Hauenstein, Karl-Heinz,
Hampel, Harald
Diffusion tensor imaging (DTI) detects white matter damage in neuro-psychiatric disorders, but data on reliability of DTI measures across more than two scanners are still missing. In this study we assessed multicenter reproducibility of DTI acquisitions based on a physical phantom as well as brain scans across 16 scanners. In addition, we performed DTI scans […]
The Montreal Cognitive Assessment (MoCA) in geriatric rehabilitation: psychometric properties and association with rehabilitation outcomes
Sweet, Lisa,
Van Adel, Mike,
Metcalf, Valerie,
Wright, Lisa,
Harley, Anne,
Leiva, René,
Taler, Vanessa
Background: Cognitive status has been reported to be an important predictor of rehabilitation outcome. The Montreal Cognitive Assessment (MoCA) was designed to overcome some of the limitations of established cognitive screening tools such as the Mini-Mental State Examination (MMSE). The purpose of this study is to evaluate the psychometric characteristics of the MoCA as a […]
Physical and psychological effects of 6-week tactile massage on elderly patients with severe dementia
Suzuki, M.,
Tatsumi, A.,
Otsuka, T.,
Kikuchi, K.,
Mizuta, A.,
Makino, K.,
Kimoto, A.,
Fujiwara, K.,
Abe, T.,
Nakagomi, T.,
Hayashi, T.,
Saruhara, T.
Tactile massage is a soft massage that improves physical relaxation and psychological well-being. The purpose of this study was to clarify the effects of a 6-week tactile massage on changes in physical and mental function, symptoms of behavioral and psychological symptoms of dementia (BPSD) among elderly patients with dementia. In addition, chromogranin A (CgA) levels […]
Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer’s disease: a pilot randomized controlled trial
Suttanon, P.,
Hill, K. D.,
Said, C. M.,
Williams, S. B.,
Byrne, K. N.,
LoGiudice, D.,
Lautenschlager, N. T.,
Dodd, K. J.
Objective: To evaluate the feasibility and safety of a home-based exercise programme for people with Alzheimer’s disease, and to provide preliminary evidence of programme effectiveness in improving balance and mobility and reducing falls risk.; Design: A randomized controlled trial.; Setting: Community.; Participants: Forty people with mild to moderate Alzheimer’s disease (mean age 81.9, SD 5.72; […]
The peaceful mind program: a pilot test of a cognitive-behavioral therapy-based intervention for anxious patients with dementia
Stanley, Melinda A.,
Calleo, Jessica,
Bush, Amber L.,
Wilson, Nancy,
Snow, A. Lynn,
Kraus-Schuman, Cynthia,
Paukert, Amber L.,
Petersen, Nancy J.,
Brenes, Gretchen A.,
Schulz, Paul E.,
Williams, Susan P.,
Kunik, Mark E.
Objectives: To assess feasibility and to conduct a preliminary evaluation of outcomes following Peaceful Mind, a cognitive-behavioral therapy-based intervention for anxiety in dementia, relative to usual care.; Design: Pilot randomized controlled trial including assessments at baseline and 3 and 6 months.; Setting: Houston, TX.; Participants: Thirty-two outpatients diagnosed with mild (47%) or moderate (53%) dementia […]
Angiotensin-converting enzyme inhibitors and Alzheimer’s disease progression in older adults: results from the Réseau sur la Maladie d’Alzheimer Français cohort
Soto, Maria E.,
Abellan van Kan, Gabor,
Nourhashemi, Fati,
Gillette-Guyonnet, Sophie,
Cesari, Matteo,
Cantet, Christelle,
Rolland, Yves,
Vellas, Bruno
Objectives: To assess whether angiotensin-converting enzyme inhibitor (ACE-I) treatment is associated with less cognitive decline in older adults with Alzheimer’s disease (AD) than in those using other hypertensive or no drugs.; Design: Four-year prospective multicenter cohort study with a biannual assessment.; Setting: Memory clinics from 16 university hospitals in France.; Participants: Community-dwelling older adults with […]
Assessment of cognition in mild cognitive impairment: a comparative study
Snyder, Peter J.,
Jackson, Colleen E.,
Petersen, Ronald C.,
Khachaturian, Ara S.,
Kaye, Jeffrey,
Albert, Marilyn S.,
Weintraub, Sandra
The demand for rapidly administered, sensitive, and reliable cognitive assessments that are specifically designed for identifying individuals in the earliest stages of cognitive decline (and to measure subtle change over time) has escalated as the emphasis in Alzheimer’s disease clinical research has shifted from clinical diagnosis and treatment toward the goal of developing presymptomatic neuroprotective […]