This database contains 366 studies, archived under the term: "methods"
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Subjective report of word-finding and memory deficits in normal aging and dementia
Calley, Clifford S.,
Tillman, Gail D.,
Womack, Kyle,
Moore, Patricia,
Hart, John, Jr.,
Kraut, Michael A.
Objective: Compare subjective reports of both memory and word-finding deficits to clinical diagnosis and objective neuropsychological testing.; Background: With the increasing number of aging individuals with cognitive impairments, effective screening measures would improve the likelihood of detection. Subjective reports of symptoms are typically obtained in clinical settings, yet the validity of these reports is relatively […]
Effects of cholinesterase inhibitors on visual attention in drivers with Alzheimer disease
Daiello, Lori A.,
Ott, Brian R.,
Festa, Elena K.,
Friedman, Michael,
Miller, Lindsay A.,
Heindel, William C.
Objective: We conducted a combined observational cohort and case-control study in patients with Alzheimer disease (AD) to assess the effects of acetylcholinesterase inhibitor (ChEI) treatment on cognitive functions important for driving.; Methods: Performance of 24 outpatients with newly diagnosed (untreated) early-stage AD was compared before beginning ChEI (pre-ChEI) and after 3 months of therapy (post-ChEI) […]
Autoimmune dementia: clinical course and predictors of immunotherapy response
Flanagan, Eoin P.,
McKeon, Andrew,
Lennon, Vanda A.,
Boeve, Bradley F.,
Trenerry, Max R.,
Tan, K. Meng,
Drubach, Daniel A.,
Josephs, Keith A.,
Britton, Jeffrey W.,
Mandrekar, Jayawant N.,
Lowe, Val,
Parisi, Joseph E.,
Pittock, Sean J.
Objective: To define the diagnostic characteristics and predictors of treatment response in patients with suspected autoimmune dementia.; Patients and Methods: Between January 1, 2002, and January 1, 2009, 72 consecutive patients received immunotherapy for suspected autoimmune dementia. Their baseline clinical, radiologic, and serologic characteristics were reviewed and compared between patients who were responsive to immunotherapy […]
A telephone intervention for dementia caregivers: background, design, and baseline characteristics
Tremont, Geoffrey,
Davis, Jennifer,
Papandonatos, George D.,
Grover, Christine,
Ott, Brian R.,
Fortinsky, Richard H.,
Gozalo, Pedro,
Bishop, Duane S.
Family caregivers of individuals with dementia are at heightened risk for emotional and mental health problems. Many caregivers do not seek assistance or become isolated in their caregiving role. Multi-component interventions have demonstrated efficacy for reducing emotional distress and burden, although these approaches are potentially costly and are not widely accessible. In response to these […]
Self-management in early-stage dementia: a pilot randomised controlled trial of the efficacy and cost-effectiveness of a self-management group intervention (the SMART study)
Quinn, Catherine,
Anderson, Daniel,
Toms, Gill,
Whitaker, Rhiannon,
Edwards, Rhiannon Tudor,
Jones, Carys,
Clare, Linda
Background: The possibility of living well with a long-term condition has been identified as centrally relevant to the needs of people living with dementia. Growing numbers of people with early-stage dementia are contributing accounts that emphasise the benefits of actively engaging in managing the condition. Self-management interventions share the common objectives of educating about the […]
Systematic care for caregivers of people with dementia in the ambulatory mental health service: designing a multicentre, cluster, randomized, controlled trial
Spijker, Anouk,
Verhey, Frans,
Graff, Maud,
Grol, Richard,
Adang, Eddy,
Wollersheim, Hub,
Vernooij-Dassen, Myrra
Background: Care for people with dementia and their informal caregivers is a challenging aim in healthcare. There is an urgent need for cost-effective support programs that prevent informal caregivers of people with dementia from becoming overburdened, which might result in a delay or decrease of patient institutionalization. For this reason, we have developed the Systematic […]