Kersten, H., Molden, E., Tolo, I. K., Skovlund, E., Engedal, K., Wyller, T. B.

Background: Observational studies report a relationship between anticholinergic drug scale (ADS) score and cognitive function. This study investigated whether a reduced ADS score improved cognitive function in a frail elderly population.; Methods: This randomized, controlled, single-blinded trial, recruited long-term residents with an ADS score of greater than or equal to 3 from 22 nursing homes […]

Hyttinen, Laura, TuulioHenriksson, Annamari, Vuorio, Alpo F., Kuosmanen, Noora, Härkänen, Tommi, Koskinen, Seppo, Strandberg, Timo E.

The cognitive status of aged familial hypercholesterolemia (FH) patients treated with long-term statin therapy was compared with that of population controls. A comprehensive cohort of 43 elderly (age > or = 65 years) patients all with the same FH North Karelia mutation living in North Karelia (eastern Finland) was identified, 37 of whom (aged 65 […]

Greenaway, M. C., Duncan, N. L., Smith, G. E.

Objective: Individuals with amnestic mild cognitive impairment (MCI) have few empirically based treatment options for combating their memory loss. This study sought to examine the efficacy of a calendar/notebook rehabilitation intervention, the memory support system (MSS), for individuals with amnestic MCI.; Methods: Forty individuals with single domain amnestic MCI and their program partners were randomized […]

Goudour, Amandine, Samson, Séverine, Bakchine, Serge, Ehrlé, Nathalie

The purpose of this study was to assess the effects of semantic stimulation of Alzheimer’s patients on semantic memory comparatively to psychological support. We conducted semantic training with two target categories (musical instruments and human actions), because these concepts were massively failed in previous data collected in Alzheimer’s disease. Ten patients (57-78 year old, MMSE […]

Chapman, Robert M., Mapstone, Mark, Gardner, Margaret N., Sandoval, Tiffany C., McCrary, John W., Guillily, Maria D., Reilly, Lindsey A., DeGrush, Elizabeth

We analyzed verbal episodic memory learning and recall using the Logical Memory (LM) subtest of the Wechsler Memory Scale-III to determine how gender differences in AD compare to those seen in normal elderly and whether or not these differences impact assessment of AD. We administered the LM to both an AD and a Control group, […]

Boudreaux, Emily O., Cherry, Katie E., Elliott, Emily M., Hicks, Jason L.

Eight participants with probable Alzheimer’s disease (AD) were trained to recall names of countries using the spaced-retrieval memory intervention. Six training sessions were administered on alternate days over a 2-week period. Half of the participants studied a target country alone and the other half studied a target country along with eight distractor countries. Training stimuli […]

Berr, Claudine, Portet, Florence, Carrière, Isabelle, Akbaraly, Tasnime N., Feart, Catherine, Gourlet, Véronique, Combe, Nicole, Barberger-Gateau, Pascale, Ritchie, Karen

Background: Olive oil is a major component of the Mediterranean diet suggested to be beneficial to counteract Alzheimer’s disease.; Aim Of the Study: Our objective was to examine the association between olive oil use, cognitive deficit and cognitive decline in a large elderly population.; Methods: We followed 6,947 subjects with a brief baseline food frequency […]