Lam, Linda Chiu-Wa, Chan, Wai-chi, Leung, Tony, Fung, Ada Wai-Tung, Leung, Edward Man-Fuk

Background: Epidemiologic evidence suggests that cognitive and physical activities are associated with better cognition in late life. The present study was conducted to examine the possible benefits of four structured lifestyle activity interventions and compare their effectiveness in optimizing cognition for older adults with mild cognitive impairment (MCI).; Method and Findings: This was a 12-month […]

Anstey, Kaarin J., Bahar-Fuchs, Alex, Herath, Pushpani, Rebok, George W., Cherbuin, Nicolas

Background: Disappointing results from clinical trials of disease-modifying interventions for Alzheimer’s dementia (AD), along with reliable identification of modifiable risk factors in mid life from epidemiological studies, have contributed to calls to invest in risk-reduction interventions. It is also well known that AD-related pathological processes begin more than a decade before the development of clinical […]

McCurry, Susan M., Pike, Kenneth C., Vitiello, Michael V., Logsdon, Rebecca G., Larson, Eric B., Teri, Linda

Objectives: To test the effects of walking, light exposure, and a combination intervention (walking, light, and sleep education) on the sleep of persons with Alzheimer’s disease (AD).; Design: Randomized, controlled trial with blinded assessors.; Setting: Independent community living.; Participants: One hundred thirty-two people with AD and their in-home caregivers.; Interventions: Participants were randomly assigned to […]

Jiang, Changchuan, Xu, Yong

Objectives: The ability to perform instrumental activities of daily living (IADL) is thought to be relatively intact for people with mild cognitive impairment (MCI). Doing housework as part of IADL is an important skill needed for older people to live independently and successfully. A limited number of studies explore the association between MCI and doing […]

Middleton, Laura E., Barnes, Deborah E., Lui, Li-Yung, Yaffe, Kristine

Objective: To determine how physical activity at various ages over the life course is associated with cognitive impairment in late life.; Design: Cross-sectional study.; Setting: Four U.S. sites.; Participants: Nine thousand three hundred forty-four women aged 65 and older (mean 71.6) who self-reported teenage, age 30, age 50, and late-life physical activity.; Measurements: Logistic regression […]

Buettner, Linda L., Fitzsimmons, Suzanne

This project tested a 12-week health promotion course for older adults with early-stage dementia. In a quasi-experimental design, participants were assigned by site to intervention group or control group and evaluated at two time points. Mini-Mental State Examination scores, Geriatric Depression Scale scores, health behaviors, plus several measures of psychological well-being were used in this […]

Berr, Claudine, Portet, Florence, Carrière, Isabelle, Akbaraly, Tasnime N., Feart, Catherine, Gourlet, Véronique, Combe, Nicole, Barberger-Gateau, Pascale, Ritchie, Karen

Background: Olive oil is a major component of the Mediterranean diet suggested to be beneficial to counteract Alzheimer’s disease.; Aim Of the Study: Our objective was to examine the association between olive oil use, cognitive deficit and cognitive decline in a large elderly population.; Methods: We followed 6,947 subjects with a brief baseline food frequency […]