Connell, Cathleen M., Janevic, Mary R.

Despite the importance of self-care for dementia caregivers, few interventions have included a focus on health behaviors. This study reports outcomes of a telephone-based exercise intervention designed for women caring for a spouse with dementia. Caregivers (N = 137) were randomized to intervention or control conditions. Participants with at- or below-median exercise scores at baseline […]

Anstey, Kaarin J., Bahar-Fuchs, Alex, Herath, Pushpani, Rebok, George W., Cherbuin, Nicolas

Background: Disappointing results from clinical trials of disease-modifying interventions for Alzheimer’s dementia (AD), along with reliable identification of modifiable risk factors in mid life from epidemiological studies, have contributed to calls to invest in risk-reduction interventions. It is also well known that AD-related pathological processes begin more than a decade before the development of clinical […]

McCurry, Susan M., Pike, Kenneth C., Vitiello, Michael V., Logsdon, Rebecca G., Larson, Eric B., Teri, Linda

Objectives: To test the effects of walking, light exposure, and a combination intervention (walking, light, and sleep education) on the sleep of persons with Alzheimer’s disease (AD).; Design: Randomized, controlled trial with blinded assessors.; Setting: Independent community living.; Participants: One hundred thirty-two people with AD and their in-home caregivers.; Interventions: Participants were randomly assigned to […]

Quinn, Catherine, Anderson, Daniel, Toms, Gill, Whitaker, Rhiannon, Edwards, Rhiannon Tudor, Jones, Carys, Clare, Linda

Background: The possibility of living well with a long-term condition has been identified as centrally relevant to the needs of people living with dementia. Growing numbers of people with early-stage dementia are contributing accounts that emphasise the benefits of actively engaging in managing the condition. Self-management interventions share the common objectives of educating about the […]

Richard, E., Gouw, A. A., Scheltens, P., van Gool, W. A.

Background and Purpose: White matter lesions (WMLs) and cerebral infarcts are common findings in Alzheimer disease and may contribute to dementia severity. WMLs and lacunar infarcts may provide a potential target for intervention strategies. This study assessed whether multicomponent vascular care in patients with Alzheimer disease with cerebrovascular lesions slows progression of WMLs and prevents […]

Middleton, Laura E., Barnes, Deborah E., Lui, Li-Yung, Yaffe, Kristine

Objective: To determine how physical activity at various ages over the life course is associated with cognitive impairment in late life.; Design: Cross-sectional study.; Setting: Four U.S. sites.; Participants: Nine thousand three hundred forty-four women aged 65 and older (mean 71.6) who self-reported teenage, age 30, age 50, and late-life physical activity.; Measurements: Logistic regression […]

Buettner, Linda L., Fitzsimmons, Suzanne

This project tested a 12-week health promotion course for older adults with early-stage dementia. In a quasi-experimental design, participants were assigned by site to intervention group or control group and evaluated at two time points. Mini-Mental State Examination scores, Geriatric Depression Scale scores, health behaviors, plus several measures of psychological well-being were used in this […]