Gies, Cheryl, Pierce, Linda, Steiner, Victoria, van der Bijl, Joan, Salvador, Diane

Purpose and Design: Most of the 5.4 million Americans with dementia are cared for by family members who experience care needs and time constraints. This quasi-experimental study examined the experience of using a psychosocial assessment instrument to understand caregiver needs delivered in an interview versus a self-administered web-based format.; Methods: Ten family caregivers were randomized […]

de Rotrou, Jocelyne, Cantegreil, Inge, Faucounau, Véronique, Wenisch, Emilie, Chausson, Catherine, Jegou, David, Grabar, Sophie, Rigaud, Anne-Sophie

Objective: The Aide dans la Maladie d’Alzheimer (AIDMA) study was conducted to determine whether a psycho-educational programme (PEP) for primary caregivers in addition to standard anti-dementia drugs for patients improves caregivers’ psychological condition and patients’ activities of daily life.; Method: Multicentre randomised controlled intervention trial. One hundred and sixty-seven dyads ‘patient-caregiver’ were recruited from 15 […]

Buerger, Katharina, Frisoni, Giovanni, Uspenskaya, Olga, Ewers, Michael, Zetterberg, Henrik, Geroldi, Cristina, Binetti, Giuliano, Johannsen, Peter, Rossini, Paolo Maria, Wahlund, Lars-Olof, Vellas, Bruno, Blennow, Kaj, Hampel, Harald

Background: Alzheimer’s Disease Neuroimaging Initiatives (“ADNI”) aim to validate neuroimaging and biochemical markers of Alzheimer’s disease (AD). Data of the pilot European-ADNI (E-ADNI) biological marker programme of cerebrospinal fluid (CSF) and plasma candidate biomarkers are reported.; Methods: Six academic EADC centres recruited 49 subjects (healthy controls, subjects with mild cognitive impairment (MCI) and AD). We […]

Becker, James T., Dew, Mary Amanda, Aizenstein, Howard J., Lopez, Oscar L., Morrow, Lisa, Saxton, Judith, Tárraga, Lluís

Purpose: Mild cognitive deficits associated with HIV disease can affect activities of daily living, so interventions that reduce them may have a long-term effect on quality of life. We evaluated the feasibility of a cognitive stimulation program (CSP) to improve neuropsychological test performance in HIV disease.; Methods: Sixty volunteers (30 HIV-infected) participated. The primary outcome […]