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This database contains 148 studies, archived under the term: "epidemiology"

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Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women’s Health Initiative randomized trials

Importance: Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention.; Objective: To report a comprehensive, integrated overview of findings from the 2 Women’s Health Initiative (WHI) hormone therapy trials with extended postintervention follow-up.; Design, Setting, and Participants: A total of 27,347 postmenopausal women aged 50 […]

Maintenance of health and relief for caregivers of elderly with dementia by using “initial case management”: experiences from the Lighthouse Project on Dementia, Ulm, ULTDEM-study

Background: When facing the well-known demographic development with an increasing number of people suffering from dementia, there is a need of programmes to support nursing relatives and care at home. Many support services have been established in the past few years but they are rarely used by the relatives and the patients. The purpose of […]

The KICA Screen: the psychometric properties of a shortened version of the KICA (Kimberley Indigenous Cognitive Assessment)

Aim: To describe the development and psychometric properties of the KICA (Kimberley Indigenous Cognitive Assessment) Screen.; Methods: A short 10-item version of the KICA, the KICA screen was developed from original data of 363 Aboriginal people. The KICA Screen was subsequently independently validated in a non-random sample of 55 people living in Northern Queensland.; Results: […]

Optimal blood pressure for cognitive function: findings from an elderly African-American cohort study

Objectives: To report the results from a prospective cohort study on the association between blood pressure (BP) and cognitive function in elderly African Americans.; Design: Prospective cohort study conducted from 1997 to 2009.; Setting: Community-based study in Indianapolis.; Participants: African Americans aged 65 years or older (N = 3,145).; Measurements: At each assessment, participant cognitive […]

Evaluation of a computer-assisted errorless learning-based memory training program for patients with early Alzheimer’s disease in Hong Kong: a pilot study

Background: Improving the situation in older adults with cognitive decline and evidence of cognitive rehabilitation is considered crucial in long-term care of the elderly. The objective of this study was to implement a computerized errorless learning-based memory training program (CELP) for persons with early Alzheimer’s disease, and to compare the training outcomes of a CELP […]

Memantine is associated with longer survival than donepezil in a Veterans Affairs prescription database, 1997 to 2008

Alzheimer’s disease (AD) shortens life-expectancy, but the effects of pharmacological treatments for this disorder on mortality have not been studied. We compared two commonly prescribed medications, donepezil and memantine, with respect to the length of survival of veterans presumed to have AD. The Computerized Medical Records System at the Veterans Affairs Palo Alto Health Care […]

Irritable bowel syndrome correlates with increased risk of Parkinson’s disease in Taiwan

This study investigated whether an association exists between irritable bowel syndrome (IBS) and the risk of Parkinson’s disease. This is a retrospective cohort study using the dataset of the Taiwan National Health Insurance Program from 2000 to 2010. We identified 23,875 patients (aged 20 years or older) with newly diagnosed IBS as the IBS group […]

A randomized controlled trial of dietetic interventions to prevent cognitive decline in old age hostel residents

Background/objectives: To examine whether dietary interventions promote intakes of fruit, vegetable, fish and lower salt intake were effective in preventing cognitive decline in older people. Dietary factors have been associated with cognitive function in older people.; Subjects/methods: A total of 429 non-demented subjects in 14 old age hostels, with an average age of 83 years, […]

The impact of TCARE® on service recommendation, use, and caregiver well-being

Purpose Of the Study: Findings are reported from a study that examined the effects of the Tailored Caregiver Assessment and Referral (TCARE®) protocol, a care management process designed to help family caregivers, on care planning and caregiver outcomes.; Design and Methods: A longitudinal, randomized controlled trial was conducted with 97 caregivers enrolled in a demonstration […]

Mediterranean diet and cognitive function: a French study

Background: Evidence on the association between Mediterranean diet (MedDiet) adherence and cognition is presently inconsistent.; Objectives: The aims of this study were to investigate the association between midlife MedDiet adherence and cognitive performance assessed 13 y later among participants in the SU.VI.MAX (Supplementation with Vitamins and Mineral Antioxidants) study and to test the hypothesis of […]

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